Evidence map›Paper›PMID 40453586›Full record

SynthesisFrontiers in endocrinology2025

Review of Mendelian randomization studies on common male-specific diseases.

Qixin Pang, Zhe Chang, Hao Liu, Jianshe Chen, Sicheng Ma, Chenming Zhang, Zixue Sun

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qixin Pang *Traditional Chinese Medicine (ZHONG JING) School, Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China.
Zhe Chang *School of Foreign Languages, Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China.
Hao LiuQueen Mary College, Nanchang University, Nanchang, Jiangxi, China.
Jianshe ChenReproductive Medicine Department, Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan, China.
Sicheng MaThe Second Clinical Medical School, Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China.
Chenming ZhangThe Second Clinical Medical School, Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China.
Zixue SunReproductive Medicine Department, Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although numerous Mendelian randomization studies on risk factors have been conducted in male medicine, a systematic synthesis of these findings is still lacking. This review searched relevant literature in PubMed and the Web of Science published before May 2024; systematically summarized the progress in the application of Mendelian randomization in male infertility, erectile dysfunction, prostate cancer, and prostatitis; summarized and classified the risk factors affecting men's health, such as the gut microbiota, modifiable risk factors and related diseases; and presented some problems and solutions that were presented in these studies. This information offers valuable insights into the etiology and pathogenesis of male-specific diseases.

Indexed as

Erectile DysfunctionInfertility, MaleMendelian Randomization AnalysisProstatic NeoplasmsProstatitisGastrointestinal MicrobiomeGenetic Predisposition to DiseaseHumansMaleRisk Factorserectile dysfunctionmale infertilityMendelian randomizationprostate cancerprostatitis

Identifiers

PMID40453586
PMCPMC12122330

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.