Evidence map›Paper›PMID 40453947›Full record

ArticleVeterinary world2025

Hematological changes in anemic dairy calves treated with a hematinic complex.

Roberto González-Garduño, Fleider Leiser Peña-Escalona, Rocío Hernández-Díaz, Carlos Luna-Palomera, Ema de Jesús Maldonado-Siman, Ever Del Jesus Flores-Santiago, Alfonso J Chay-Canul

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Article in Veterinary world, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roberto González-GarduñoSouth-Southeast Regional University Unit, Autonomous University of Chapingo, Teapa, Tabasco, Mexico.
Fleider Leiser Peña-EscalonaBachelor's Degree in Business Administration and Management, Polytechnic University of Texcoco, Estado de Mexico. Mexico.
Rocío Hernández-DíazDepartment of Engineering, Technological Institute of the Altiplano of Tlaxcala, National Technology of Mexico, San Diego, Xocoyucan, Tlaxcala, Mexico.
Carlos Luna-PalomeraAcademic Division of Agricultural Sciences, Juarez Autonomous University of Tabasco, Villahermosa, Tabasco, Mexico.
Ema de Jesús Maldonado-SimanPostgraduate in Animal Production, Autonomous University of Chapingo, Texcoco, Estado de Mexico. Mexico.
Ever Del Jesus Flores-SantiagoSouth-Southeast Regional University Unit, Autonomous University of Chapingo, Teapa, Tabasco, Mexico.
Alfonso J Chay-CanulAcademic Division of Agricultural Sciences, Juarez Autonomous University of Tabasco, Villahermosa, Tabasco, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Weaning is a critical period in calf development, particularly under tropical conditions where nutritional stress and parasitic infestations can precipitate anemia. Anemia compromises growth and survival; yet, few studies have evaluated the effectiveness of hematinic therapy in anemic calves before weaning in tropical systems. This study aimed to assess hematological responses in anemic dairy calves treated with a hematinic complex and to establish anemia thresholds based on hematological indices in healthy calves raised under tropical conditions. Materials and Methods: A total of 22 Holstein × Zebu calves were studied from January to April 2024 in Tabasco, Mexico. Calves were grouped as healthy (n = 10; hematocrit [HCT] >24%) or anemic (n = 12; HCT <24%). The anemic group received an intramuscular hematinic complex for 5 consecutive days and three additional doses at day 42. Hematological parameters were measured every 21 days using an automated analyzer. Anemia thresholds were defined from the healthy group using mean ± 2 standard deviations. Data were analyzed using a repeated-measures design over time. Results: Anemia thresholds were determined as HCT <21.3%, hemoglobin (HGB) <7.5 g/dL, and red blood cell (RBC) <5.4 × 10 Conclusion: The administration of a hematinic complex effectively restored hematological parameters in anemic calves within 42 days, with sustained improvement following a second application. This intervention is recommended as part of pre-weaning health protocols to mitigate anemia-related growth setbacks in tropical cattle systems.

Indexed as

anemiacalveshaematocrithaemoglobinhematinic complexred blood cellstropical cattle systems

Identifiers

PMID40453947
PMCPMC12123272

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.