Evidence map›Paper›PMID 40454302›Full record

Trial reportClinical interventions in aging2025

Intervening on Calorie Intake or Eating Timing in Older Adults: Lessons Learned in the Healthy Aging and Late-Life Outcomes Randomized Controlled Pilot Trial.

Jason Fanning, W Jack Rejeski, Barbara J Nicklas, Stephen B Kritchevsky, Michael E Miller, Denise K Houston, Michael P Walkup, Kimberly Kennedy, Cynthia L Stowe, Sherri Ford and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jason FanningDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.ORCID 0000-0002-5527-1698
W Jack RejeskiDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.ORCID 0000-0003-2281-4649
Barbara J NicklasDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Stephen B KritchevskyDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Michael E MillerDepartment of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Denise K HoustonDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Michael P WalkupDepartment of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Kimberly KennedyDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Cynthia L StoweDepartment of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0002-1887-3294
Sherri FordDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.ORCID 0000-0002-3162-2174
Dixie YowDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
HALLO-P Investigators

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI STEPHEN B. KRITCHEVSKY · 2002 to 2026
$36.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
The Mobile Devices for Meal Timing (MD4MT) Study: A supplement to HALLO-P using multiple wearable devise to improve accuracy in meal timing for older adults2U01AG073240 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KRITCHEVSKY, STEPHEN B., MILLER, MICHAEL E. · 2021 to 2024
$4.4M
NCATS NIH HHS UL1 TR001420NIA NIH HHS P30 AG021332NIA NIH HHS U01 AG073240
6 · The paper itself

Abstract

Purpose: The Healthy Aging and Late Life Outcomes Pilot (HALLO-P) trial was designed to pilot in-person and remotely delivered caloric restriction (CR and RCR respectively) and time restricted eating (TRE) in preparation for a long-term multi-site clinical trial. Herein, we describe the development and execution of these behavioral interventions with a focus on lessons learned and post-study questionnaire data. Patients and Methods: Participants were community-dwelling older (60+ yrs) adults with obesity or overweight with an indication for weight loss. Participants were randomized to 9 months of group-based CR, RCR, or TRE supported by self-monitoring technologies [ie, a tablet application paired with an activity monitor (all) and wireless scale (CR and RCR)]. Intervention staff recorded attendance at sessions and noted intervention-related lessons learned as they arose. Upon completion of the study period, participants were asked to complete a series of Likert-type and open-ended questions related to their experiences in the trial. Results: Participants (N = 90; 67.19 ± 4.91 years) attended 84.4% of sessions on average, engaged with study technologies 96.4% of days, and provided daily weights on >4 days per week across the study (CR and RCR only). Participants reported high satisfaction with the program, with RCR participants being significantly more likely than TRE participants to report being satisfied with their program overall (100% vs 75%, p < 0.01), intending to continue their dietary change post-intervention (97% vs 63%, p < 0.01), and being willing to sustain their dietary approach and engage with study technologies over a 5-year period (88% vs 61%, p < 0.01). Open-ended feedback underscored the value of the group-based structure of the program and remote delivery to reduce travel burden, the need for reduced burden associated with food logging, and the need to identify methods for enhancing perceived value of TRE among older adults. Conclusion: An intervention designed to promote CR, primarily delivered remotely and supported by self-monitoring technology, is both feasible and acceptable to many older adults.

Indexed as

Caloric RestrictionEnergy IntakeFeeding BehaviorHealthy AgingObesityOverweightAgedFemaleHumansIndependent LivingMaleMiddle AgedPilot ProjectsWeight Lossagingbehaviorobesitypilottechnology

Identifiers

PMID40454302
PMCPMC12123093

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.