ReviewMikrochimica acta2025
Nanomaterial-enhanced ambient ionization for miniature mass spectrometry: toward high-performance on-site detection.
Review in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Rapid and Green Extraction of Food Contaminants: Integrating Advanced Porous Materials and Miniaturized Functional Platforms for Chromatographic and Mass Spectrometric Analysis.Comprehensive reviews in food science and food safety · 2026Review
- A pilot study of a novel portable mass spectrometer for rapid, simultaneous detection of multiple anesthetic drug concentrations.Frontiers in veterinary science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Mass spectrometry (MS), which is renowned for its high sensitivity and molecular specificity, serves as a cornerstone of modern analytical chemistry. However, the field applications of MS are constrained by bulky instrumentation and operational complexity. The integration of miniaturized MS with ambient ionization has revolutionized analytical workflows, enabling "sampling-ionization-detection" platforms that have shifted paradigms from laboratory-based analysis to on-site point-of-care testing. This has led to promising applications in food safety, environmental monitoring, and clinical diagnostics. Despite these advancements, challenges such as matrix interference and insufficient sensitivity persist. To address these limitations, the structural and surface properties of nanomaterials can be leveraged and engineered, offering multidimensional enhancement strategies across MS workflows that provide improved sensitivity and mitigate matrix effects. This review summarizes the developments over the past five years in the utilization of nanomaterials coupled with ambient ionization techniques for sample pretreatment and ionization optimization. Moreover, the synergy of these strategies with miniature MS systems is systematically highlighted for food safety, biomarker detection, and environmental pollutant determination. By bridging materials science, sensor technology, and diagnostics, these multidisciplinary efforts have accelerated the development of intelligent, portable analytical platforms, paving the way for precision medicine and next-generation field-deployable diagnostics. The convergence of nanomaterial innovations, sensor miniaturization, and diagnostic advancements underscores the transformative potential of these developments for the real-time, on-site detection of trace analytes in complex matrices.
Indexed as
Identifiers
40455291What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.