Evidence map›Paper›PMID 40456615›Full record

SynthesiseNeuro2025

Gene Variants Related to Primary Familial Brain Calcification: Perspectives from Bibliometrics and Meta-Analysis.

Dehao Yang, Yangguang Lu, Honghao Huang, Yiqun Chen, Zihan Jiang, Ruotong Yao, Yiran Bu, Yu Li, Zhidong Cen, Wei Luo

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in eNeuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dehao YangDepartment of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.ORCID https://orcid.org/0000-0002-4129-9761
Yangguang LuThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou 325035, China.
Honghao HuangDepartment of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Yiqun ChenThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou 325035, China.
Zihan JiangThe Second School of Medicine, Wenzhou Medical University, Wenzhou 325035, China.
Ruotong YaoThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou 325035, China.
Yiran BuThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou 325035, China.
Yu LiThe Second School of Medicine, Wenzhou Medical University, Wenzhou 325035, China.
Zhidong CenDepartment of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China luoweirock@zju.edu.cn cenzd@zju.edu.cn.
Wei LuoDepartment of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China luoweirock@zju.edu.cn cenzd@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genetic role and specific effects of primary familial cerebral calcification (PFBC) are still unclear. We aim to analyze bibliometric features in studies related to PFBC, investigate variant detection rates in patients with brain calcifications, and examine the phenotypic characteristics of PFBC patients. A comprehensive search of studies on the genetic effects of PFBC up until December 31, 2024, was conducted across Web of Science, PubMed, Embase, and Scopus. A random-effects meta-analysis combined variant detection rates for genes

Indexed as

BibliometricsCalcinosisGenetic VariationNeurodegenerative DiseasesBasal Ganglia DiseasesHumansSodium-Phosphate Cotransporter Proteins, Type IIISLC20A2 protein, humanSodium-Phosphate Cotransporter Proteins, Type IIIbibliometricsFahr’s diseasegene variantsmeta-analysisprimary familial brain calcification

Identifiers

PMID40456615
PMCPMC12186716

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.