Evidence map›Paper›PMID 40456706›Full record

Observational studyRenal failure2025

A machine learning-based prediction model for sepsis-associated delirium in intensive care unit patients with sepsis-associated acute kidney injury.

Shuangjiang Yu, Xuming Pan, Manyuan Zhang, Jiancheng Zhang, Danlei Chen

Abstract readObservational Study
In one paragraph

Observational study in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuangjiang YuDepartment of Emergency, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Xuming PanDepartment of Emergency, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Manyuan ZhangDepartment of Emergency, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Jiancheng ZhangDepartment of Emergency, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Danlei ChenDepartment of Emergency, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis-associated acute kidney injury (SA-AKI) patients in the ICU often suffer from sepsis-associated delirium (SAD), which is linked to unfavorable outcomes. This research aimed to develop a machine learning-based model for early SAD prediction in SA-AKI patients. Data was sourced from the Medical Information Mart for Intensive Care IV (MIMIC-IV) and eICU Collaborative Research Database (eICU-CRD). Various models, including logistic regression, extreme gradient boosting (XGBoost), random forest, k-nearest neighbors, support vector machine, decision tree, and naive Bayes, were constructed and evaluated. The XGBoost model emerged as the best, with an internal validation AUROC of 0.775 and an external validation AUROC of 0.687. Unlike traditional delirium assessments, this model enables earlier SAD prediction and is suitable for patients who are hard to assess conventionally.

Indexed as

Acute Kidney InjuryPredictive Learning ModelsSepsisSepsis-Associated EncephalopathyAgedAged, 80 and overArea Under CurveBayes TheoremDatabases, FactualFemaleHumansIntensive Care UnitsLogistic ModelsMaleMiddle AgedPredictive Value of TestseICU-CRD databasemachine learningMIMIC-IV databasepredictive modelsepsis-associated acute kidney injurysepsis-associated delirium

Identifiers

PMID40456706
PMCPMC12131538

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.