Evidence map›Paper›PMID 40456729›Full record

ArticleNature communications2025

Concept transfer of synaptic diversity from biological to artificial neural networks.

Martin Hofmann, Moritz Franz Peter Becker, Christian Tetzlaff, Patrick Mäder

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martin HofmannData-intensive Systems and Visualization Group (dAI.SY), Technische Universität Ilmenau, Max-Planck-Ring 14, Ilmenau, 98693, Thuringia, Germany. martin.hofmann@tu-ilmenau.de.ORCID http://orcid.org/0000-0002-4440-3317
Moritz Franz Peter BeckerGroup of Computational Synaptic Physiology, Department for Neuro- and Sensory Physiology, University Medical Center Göttingen, Humboldtallee 23, Göttingen, 37073, Lower Saxony, Germany.ORCID http://orcid.org/0000-0002-4287-5732
Christian TetzlaffGroup of Computational Synaptic Physiology, Department for Neuro- and Sensory Physiology, University Medical Center Göttingen, Humboldtallee 23, Göttingen, 37073, Lower Saxony, Germany.
Patrick MäderData-intensive Systems and Visualization Group (dAI.SY), Technische Universität Ilmenau, Max-Planck-Ring 14, Ilmenau, 98693, Thuringia, Germany.ORCID http://orcid.org/0000-0001-6871-2707

Funding

Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research) 01IS20062Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research) FKZ 01 IS 22 093 A-EBundesministerium für Ernährung und Landwirtschaft (Federal Ministry of Food and Agriculture) 2819NA106Carl-Zeiss-Stiftung (Carl Zeiss Foundation) P2022-08-006Deutsche Forschungsgemeinschaft (German Research Foundation) TE 1172/7-1, SFB1286 subprojects C01, Z01
6 · The paper itself

Abstract

Recent developments in artificial neural networks have drawn inspiration from biological neural networks, leveraging the concept of the artificial neuron to model the learning abilities of biological nerve cells. However, while neuroscience has provided new insights into the mechanisms of biological neural networks, only a limited number of these concepts have been directly applied to artificial neural networks, with no guarantee of improved performance. Here, we address the discrepancy between the inhomogeneous and dynamic structures of biological neural networks and the largely homogeneous and fixed topologies of artificial neural networks. Specifically, we demonstrate successful integration of concepts of synaptic diversity, including spontaneous spine remodeling, synaptic plasticity diversity, and multi-synaptic connectivity, into artificial neural networks. Our findings reveal increased learning speed, prediction accuracy, and resilience to gradient inversion attacks. Our publicly available drop-in replacement code enables easy incorporation of these proposed concepts into existing networks.

Indexed as

Models, NeurologicalNeural Networks, ComputerSynapsesAnimalsHumansNerve NetNeuronal PlasticityNeurons

Identifiers

PMID40456729
PMCPMC12130319

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.