Evidence map›Paper›PMID 40457071›Full record

ArticleWorld journal of urology2025

Socioeconomic disparities and MIBC survival outcome-An analysis of a statewide cohort.

Alessio Finocchiaro, Anna Tylecki, Alex Stephens, Silvia Viganó, Alessandro Bertini, Alberto Briganti, Francesco Montorsi, Andea Salonia, Giovanni Lughezzani, Nicoló Buffi and 5 more

Abstract read
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In one paragraph

Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alessio FinocchiaroVUI Center for Outcomes Research, Analysis, and Evaluation, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI, 48202, USA.
Anna TyleckiPublic Health Sciences, Henry Ford Health System, Detroit, MI, USA.
Alex StephensPublic Health Sciences, Henry Ford Health System, Detroit, MI, USA.
Silvia ViganóVUI Center for Outcomes Research, Analysis, and Evaluation, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI, 48202, USA.
Alessandro BertiniVUI Center for Outcomes Research, Analysis, and Evaluation, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI, 48202, USA.
Alberto BrigantiDivision of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Vita-Salute San Raffaele University, Milan, Italy.
Francesco MontorsiDivision of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Vita-Salute San Raffaele University, Milan, Italy.
Andea SaloniaDivision of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Vita-Salute San Raffaele University, Milan, Italy.
Giovanni LughezzaniDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Nicoló BuffiDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Vincenzo FicarraDepartment of Clinical and Experimental Medicine, Urologic Section, University of Messina, Messina, Italy.
Ettore Di TrapaniDepartment of Clinical and Experimental Medicine, Urologic Section, University of Messina, Messina, Italy.
Akshay SoodDepartment of Urology, The James Cancer Hospital and Solove Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, US.
Craig RogersVUI Center for Outcomes Research, Analysis, and Evaluation, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI, 48202, USA.
Firas AbdollahVUI Center for Outcomes Research, Analysis, and Evaluation, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI, 48202, USA. Fabdoll1@hfhs.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMuscle-invasive bladder cancer (MIBC) is an aggressive malignancy with limited survival improvements despite advancements in treatment. Socioeconomic disparities significantly affect patient outcomes, yet the Area Deprivation Index (ADI), a robust measure of socioeconomic status, has been underexplored in MIBC. This study evaluates the association between ADI and cancer-specific mortality (CSM) in MIBC. MATERIALS AND

methodsWe retrospectively reviewed patients with MIBC (≥ T2; Any N; Any M) from the Michigan Department of Health and Human Services database (2004-2019). ADI scores were assigned based on residential census block groups and stratified into quartiles, with the 4th quartile (ADI 75-100) being the most deprived. Cumulative incidence functions compared CSM between quartiles, and competing-risk regression analysis assessed the association between ADI and CSM after adjusting for covariates.

resultsAmong 6120 patients (90% Non-Hispanic Whites; median age 73 [IQR 64-81]), most resided in metropolitan areas (80%) and were insured through Medicare (35%). Patients were distributed across ADI quartiles: 437 (1st), 1442 (2nd), 2171 (3rd), and 2070 (4th). At 10 years, CSM rates were 50%, 52%, 54%, and 55% for the 1st, 2nd, 3rd, and 4th quartiles, respectively (p = 0.01). Patients in the 3rd and 4th quartiles had 1.25 (HR 1.25, 95% CI 1.07-1.47, p = 0.016) and 1.30 (HR 1.30, 95% CI 1.11-1.54, p = 0.005) higher risks of CSM than those in the 1st quartile.

conclusionsHigher ADI was associated with increased CSM in our cohort. Further studies are needed to explore potential causal mechanisms.

Indexed as

Healthcare DisparitiesHealth Status DisparitiesUrinary Bladder NeoplasmsAgedAged, 80 and overCohort StudiesFemaleHumansMaleMichiganMiddle AgedRetrospective StudiesSocioeconomic Disparities in HealthSocioeconomic FactorsSurvival RateBladder CancerMortalitySocial disparitiesSurvival

Identifiers

PMID40457071

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.