Evidence map›Paper›PMID 40457072›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

At-home 1-week hydration improves tolerance and treatment intensity of high-dose cisplatin in locally advanced head and neck cancer: a retrospective study.

Camelia Billard-Sandu, Andreea Cabulca, Elie Rassy, Gabriela Dumitrescu, Sarah Akla, Tarek Assi, Jean Zeghondy, Pierre Blanchard, Yun Gan Tao, France Nguyen and 7 more

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Camelia Billard-SanduDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France. camelia.billard@gustaveroussy.fr.
Andreea CabulcaDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France.
Elie RassyDepartement of Medical Oncology, Gustave Roussy, Villejuif, France.
Gabriela DumitrescuDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France.
Sarah AklaDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France.
Tarek AssiDepartement of Medical Oncology, Gustave Roussy, Villejuif, France.
Jean ZeghondyDepartement of Medical Oncology, Gustave Roussy, Villejuif, France.
Pierre BlanchardDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France.
Yun Gan TaoDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France.
France NguyenDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France.
Roger SunDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France.
Florian ScotteInterdisciplinary Department for the Organisation of Patient Pathways, Gustave Roussy, Villejuif, France.
Vanessa PuglissiInterdisciplinary Department for the Organisation of Patient Pathways, Gustave Roussy, Villejuif, France.
Mario Di PalmaInterdisciplinary Department for the Organisation of Patient Pathways, Gustave Roussy, Villejuif, France.
Ingrid BreuskinDepartment of Anesthesia, Surgery and Interventional-Head and Neck Surgery Service, Gustave Roussy, Villejuif, France.
Stephane TemamDepartment of Anesthesia, Surgery and Interventional-Head and Neck Surgery Service, Gustave Roussy, Villejuif, France.
Eric DeutschDepartment of Radiation Oncology, Gustave Roussy, 114 Rue Edouard Vaillant, R94805, Villejuif, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-dose cisplatin (100 mg/m

objectiveTo assess the impact of a 1-week at-home hydration protocol following each cisplatin cycle on treatment tolerance and chemotherapy dose intensity.

methodsWe conducted a retrospective analysis of patients with locally advanced head and neck cancer treated at Gustave Roussy between January 2015 and December 2020. Eligible patients received at least one cycle of high-dose cisplatin (100 mg/m

resultsA total of 494 patients were included; 470 (95%) were under 70 years old. Of these, 451 (91%) received at least 200 mg/m

Indexed as

Antineoplastic AgentsCisplatinFluid TherapyHead and Neck NeoplasmsAcute Kidney InjuryAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesAntineoplastic AgentsCisplatinChemoradiotherapyCisplatinHead and neck squamous cell carcinomaHydration protocolNephrotoxicity

Identifiers

PMID40457072

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.