Evidence map›Paper›PMID 40457267›Full record

ArticleBMC public health2025

Calculation of COVID-19 disease burden using Monte Carlo simulation with dynamic disability weights and analysis of transmission characteristics.

Wenxiu Chen, Wei An, Qun Gao, Ji Bai, Hua Li, Song Tang, Wenhui Gao, Zhe Tian, Yu Zhang, Min Yang

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenxiu ChenNational Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Wei AnNational Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China. anwei@rcees.ac.cn.
Qun GaoBeijing Center for Disease Prevention and Control, Beijing, 100013, China.
Ji BaiNational Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Hua LiNational Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Song TangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, 100021, China.
Wenhui GaoChaoyang District Center for Disease Prevention and Control of Beijing, Beijing, 100021, China.
Zhe TianNational Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Yu ZhangNational Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Min YangNational Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China. yangmin@rcees.ac.cn.

Funding

the Key Project of the Capital's Funds for Health Improvement and Research, China 2022-1G-4231the National Key Research and Development Project of China 2023YFC3041300the National Natural Science Foundation of China 22306017the National Natural Science Foundation of China 52091545
6 · The paper itself

Abstract

backgroundDisability Weights (DWs) are crucial for assessing disease burden guiding public health decision-making. For emerging health threats such as COVID-19, the absence of relevant survey data from China has led to reliance on established DW values for specific symptoms in calculating the COVID-19 disease burden. However, these values have not been updated in real-time to reflect the ongoing mutations of the virus, potentially skewing the longitudinal estimation of COVID-19's burden and compromising the accuracy of public health interventions.

methodsThis study developed a real-time estimation framework using longitudinal internet survey data to track changes in DW distributions across different populations over time. These distributions were integrated into Monte Carlo simulations to model real-time disease burden, offering robust data to support evidence-based policy decisions and optimize resource allocation.

resultsOur analysis revealed substantial variation in DW distributions across symptoms. As populations experience multiple infections and the virus evolves, the COVID-19 disease burden has converged with, and in some cases fallen below, that of influenza's. Survey data suggested an average immunity interval of approximately five months between infections. Moreover, COVID-19 has profoundly reshaped healthcare-seeking behavior and consumption patterns, with individual lifestyle factors and pre-existing health conditions contributing significantly to infection severity.

conclusionThe real-time DW estimation method proposed in this study effectively and accurately reflects the dynamic changes in the COVID-19 disease burden amidst ongoing virus mutations, providing crucial reference data for the evaluation and formulation of public health policies. Furthermore, the study provides insights into the transmission interval of COVID-19 and behavioral changes during the pandemic, offering valuable insights for the potential outbreak of future "Disease X."

Indexed as

Cost of IllnessCOVID-19Persons with DisabilitiesAdultChinaFemaleHumansLongitudinal StudiesMaleMiddle AgedMonte Carlo MethodCOVID-19Disability WeightEmerging DiseaseMonte CarloTransmission Characteristics

Identifiers

PMID40457267
PMCPMC12128244

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.