SynthesisFrontiers in public health2025
Aerobic activity significantly reduces blood pressure among hypertensive adults in Africa: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Review
- Effects of Prior Exercise Habits and Adherence on Cognitive Function, Physical Fitness, and Vascular Health in Older Adults: An Exploratory Exercise-Based Intervention Trial.Dementia and neurocognitive disorders · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sub-Saharan Africa is faced with the increasing prevalence of high blood pressure, with projections estimating that 216.8 million people will be affected by 2030. Aerobic activity has been recognized for its cardiovascular benefits. However, its effect remains under-explored, and the findings are largely inconsistent. Therefore, this review aimed to estimate the overall effect of aerobic activity on blood pressure among hypertensive adults receiving medication in Africa. Methods: Randomized clinical trials conducted in Africa and published between 2000 and September 2024 were considered eligible if they included hypertensive adults aged 18 years and older. Studies were identified through searches on PubMed, African Journal Online, Hinari, and Science Direct databases. In addition, the Cochrane risk-of-bias tool (ROBIS-2) was used for quality assessment. Results: Of the 683 articles identified, eight qualified for qualitative assessment, comprising 1,112 participants on antihypertensive medication (625 in the intervention group and 487 in the control group). The follow-up duration ranged from 6 to 16 weeks, with different aerobic modalities such as brisk walking, dance, and bicycle ergometer. These activities were performed either continuously or at different time intervals (three times per week), lasting between 30 and 60 min. The overall risk of bias was moderate, and the intensity of the training was based on VO Conclusion: Our finding shows that adherence to antihypertensive medications in addition to aerobic activity effectively reduced blood pressure among hypertensive adults in Africa, particularly at 8 weeks, with a slightly diminished effect in prolonged durations. It is, therefore, imperative to conduct further studies in this area of hypertension management. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024614250.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.