ArticleFrontiers in endocrinology2025
Triglyceride-glucose index and periodontitis: evidence from two population-based surveys.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Association Between Glyco-Lipid Seven-Factor Index, a Novel Composite Glyco-Lipid Index, and Periodontitis: A Cross-Sectional Study.International dental journal · 2026Article
- A Cross-Sectional Study Based on Deep Learning to Explore the Effect of Triglyceride/Glucose Index on Periodontitis: An Analysis Based on the Large NHANES Database.Oral health & preventive dentistry · 2026Article
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The relationship between the Triglyceride-Glucose (TyG) index and periodontitis remains unclear. This study aims to elucidate this relationship using data from two large population-based surveys. Methods: Datasets from NHANES (2009-2014) and KNHANES (2007-2018, except for 2011) were utilized. We applied multivariate logistic regression, stratified analysis, restricted cubic splines (RCS), and subgroup analyses to examine the correlation between the TyG index and periodontitis risk. The predictive value of the TyG index was assessed using receiver operating characteristic (ROC) curves. Mediation analyses investigated variables mediating this relationship. Results: The NHANES and KNHANES cohorts included 2,511 and 16,239 participants with periodontitis, respectively. After adjusting for covariates, the TyG index was significantly associated with periodontitis risk (NHANES: OR 1.19, 95%CI: 1.07-1.34; Q2 vs. Q1, OR 1.20, 95% CI: 1.02-1.42; Q4 vs. Q1, OR 1.23, 95%CI: 1.02-1.49. KNHANES: OR 1.09, 95% CI: 1.05-1.13; Q4 vs. Q1, OR 1.09, 95%CI: 1.02-1.17, Conclusions: The observational analysis reveals a significant association between the TyG index and the risk of periodontitis. Further studies are needed to clarify the underlying mechanisms.
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