ArticleFrontiers in endocrinology2025
The relationship between dietary inflammation potential, dietary oxidative balance score, and female reproductive function: a mediation analysis of obesity indicators.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Lower oxidative balance score is linked to increased miscarriage risk: findings from a case-control study.BMC pregnancy and childbirth · 2026Article
- Association of estradiol and progesterone levels on human chorionic gonadotropin day with pregnancy outcomes in IVF/ICSI fresh embryo transfer.Frontiers in endocrinology · 2026Article
- Association of Dietary Inflammation Index with Infertility Risk in US Women: A Cross-Sectional Analysis from NHANES (2013-2020).International journal of women's health · 2025Article
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Authors and funding
7 authors.
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Abstract
Background: Dietary inflammation and oxidative stress have been linked to reproductive health, and weight gain has also been found to play an important role in female reproductive function specifically. In this study we explore the effects of dietary inflammatory index (DII) and dietary oxidative balance score (DOBS) on infertility and sex hormones, and clarify the mediating role of obesity on these effects. Methods: A total of 1,774 subjects from the 2013-2016 National Health and Nutrition Examination Survey (NHANES) were selected. The DII and DOBS were determined by aggregating data on 26 and 17 dietary components obtained by dietary recall, respectively. Infertility (yes or no, self-reported in questionnaire) and serum gonadal hormones including total testosterone (TT), estradiol (E Results: The prevalence of infertility among American women of childbearing age was 12.66%. There were significant linear relationships between the DII and DOBS, and infertility and serum SHBG ( Conclusions: Dietary inflammation and oxidative stress are strongly associated with the risk of infertility and serum SHBG levels, indicating that anti-inflammatory and anti-oxidative diets may mitigate fertility disorders that result from obesity.
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