Evidence map›Paper›PMID 40458301›Full record

ArticleJournal of clinical & cellular immunology2025

Nuclear

Isatou Bah, Dima Youssef, Mary E Howell, Zhi Q Yao, Charles E McCall, Mohamed El Gazzar

Abstract read
In one paragraph

Article in Journal of clinical & cellular immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Isatou BahDepartment of Internal Medicine and Center of Excellence for Inflammation, Infectious Dieases and Immunity, East Tennessee State University College of Medicine, Johnson City, TN 37614, United States of America.
Dima YoussefDepartment of Internal Medicine and Center of Excellence for Inflammation, Infectious Dieases and Immunity, East Tennessee State University College of Medicine, Johnson City, TN 37614, United States of America.
Mary E HowellDepartment of Internal Medicine and Center of Excellence for Inflammation, Infectious Dieases and Immunity, East Tennessee State University College of Medicine, Johnson City, TN 37614, United States of America.
Zhi Q YaoDepartment of Internal Medicine and Center of Excellence for Inflammation, Infectious Dieases and Immunity, East Tennessee State University College of Medicine, Johnson City, TN 37614, United States of America.
Charles E McCallDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, United States of America.
Mohamed El GazzarDepartment of Internal Medicine and Center of Excellence for Inflammation, Infectious Dieases and Immunity, East Tennessee State University College of Medicine, Johnson City, TN 37614, United States of America.

Funding

S100A9 and MDSC development in sepsis.R35GM131692 · NIGMS · EAST TENNESSEE STATE UNIVERSITY · PI ELGAZZAR, MOHAMED A. · 2019 to 2023
$1.9M
NIGMS NIH HHS R35 GM131692
6 · The paper itself

Abstract

Expansion and accumulation of Myeloid-Derived Suppressor Cells (MDSCs) during sepsis contribute to post-sepsis immunosuppression, as these cells suppress innate and adaptive immunity. We have shown that the proinflammatory

Indexed as

Immune suppressionMyeloid-Derived Suppressor Cells (MDSCs)S100A9Sepsis

Identifiers

PMID40458301
PMCPMC12129438

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.