Evidence map›Paper›PMID 40458334›Full record

ArticleCureus2025

A Rare Incidental Discovery of an Intrapulmonary Shunt in a Young Man: A Case Report.

Varshitha T Panduranga, Mrinal J P Oble, Ammar Y Abdulfattah, Adam S Budzikowski, Samy I McFarlane, Sabu John

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Varshitha T PandurangaDepartment of Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Mrinal J P ObleDepartment of Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Ammar Y AbdulfattahDepartment of Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Adam S BudzikowskiDepartment of Cardiology, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Samy I McFarlaneDepartment of Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Sabu JohnDepartment of Cardiology, State University of New York Downstate Medical Center, Brooklyn, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An intrapulmonary shunt (IPS) occurs when blood bypasses oxygenation in the lungs, flowing directly from the right side of the heart to the left side without undergoing gas exchange. This condition is distinct from an intracardiac shunt, which involves an abnormal connection between the heart chambers or vessels, allowing atypical blood flow. In this report, we present the case of a 21-year-old man with a one-year history of persistent cough, nocturnal chest pain, nasal congestion with shortness of breath, and generalized abdominal pain. In the emergency department, his vital signs and physical examination were unremarkable. Electrocardiography (EKG) revealed sinus bradycardia with right-axis deviation and incomplete right bundle branch block pattern. Chest X-ray and routine laboratory investigations were normal. The patient was referred to cardiology for further evaluation of shortness of breath. A transthoracic echocardiogram (TTE) with a bubble study demonstrated a normal ejection fraction of 63% with no regional wall motion abnormalities. Agitated saline injected via the left antecubital vein revealed no bubbles in the left atrium during the first six cardiac cycles. However, after six cycles, a small number of bubbles appeared in the left atrium and left ventricle, indicative of an IPS. In this case report, we highlight a unique incidental finding of an IPS in a young man, emphasizing the importance of bubble study timing in distinguishing IPS from intracardiac shunts.

Indexed as

agitated saline contrast studiesechocardiogram with bubble studyintracardiac shuntingintrapulmonary shunttransthoracic echocardiogram

Identifiers

PMID40458334
PMCPMC12127709

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.