Evidence map›Paper›PMID 40458373›Full record

ArticlebioRxiv : the preprint server for biology2025

CircRNA hypomethylation in the human amygdala implicates

Tara Ghandour, Jill R Glausier, Arun Asok, Michelle R Doyle, Paola Campo, Luca Colnaghi, David A Lewis, Denise B Kandel, Eric R Kandel, Giordano de Guglielmo and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tara GhandourCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, NY, 10003, USA.
Jill R GlausierDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.
Arun AsokDepartment of Neuroscience, Columbia University, New York, NY 10032, USA.
Michelle R DoyleDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA.
Paola CampoDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA.
Luca ColnaghiDivision of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
David A LewisDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.
Denise B KandelDepartment of Psychiatry, Vagelos College of Physicians and Surgeons and Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Eric R KandelDepartment of Neuroscience, Columbia University, New York, NY 10032, USA.
Giordano de GuglielmoDepartment of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA.
Shao-Shan Carol HuangCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, NY, 10003, USA.
Philippe A MelasCenter for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, 11364 Stockholm, Sweden.ORCID 0000-0002-7889-9250

Funding

Neurpsychopharmacology-Multidisciplinary TrainingT32AA007456 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI MARISA ROBERTO · 1985 to 2026
$13.4M
Sequence, chromatin, and cellular contexts of transcription factor- DNA interaction and functionR35GM138143 · NIGMS · NEW YORK UNIVERSITY · PI Shao-shan Carol Huang · 2020 to 2026
$2.4M
Identification of Genetic Variants that Influence Compulsive Alcohol Intake in Outbred RatsR01AA030048 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Giordano De Guglielmo · 2023 to 2026
$1.7M
NIAAA NIH HHS R01 AA030048NIAAA NIH HHS T32 AA007456NIGMS NIH HHS R35 GM138143
6 · The paper itself

Abstract

Genome- and phenome-wide association studies implicate the RNA demethylase

Indexed as

alcohol use disordercircular RNAsepitranscriptomicsFKBP5m6A RNA methylation

Identifiers

PMID40458373
PMCPMC12129098

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.