ReviewFrontiers in pediatrics2025
Research progress on human adenovirus sepsis.
Review in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Pediatric adenovirus infections: 10-year clinical spectrum and predictors of severe disease with emphasis on comorbidities and coinfections.European journal of pediatrics · 2026Observational
- Genomic characterization and evolutionary dynamics of human adenovirus C (HAdV-C) in Beijing (2023-2024): insights into multiple recombination and adaptive evolution.Virus evolution · 2026Article
- Development and validation of an immune-based nomogram model for predicting severe adenovirus pneumonia in hospitalized children.Frontiers in pediatrics · 2026Article
- Monitoring human adenovirus loads in bronchoalveolar lavage fluid in non-immunocompromised children with human adenovirus pneumonia.Translational pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human adenovirus is a significant viral pathogen causing lower respiratory tract infections in children, prone to developing into severe pneumonia and systemic inflammation with a high mortality rate, especially in immunocompromised children, drawing widespread attention worldwide. Sepsis, a life-threatening organ dysfunction caused by a dysregulated inflammatory response to infection, has historically been focused on bacterial origins. However, nearly all viruses can cause sepsis, which is often underestimated in clinical settings. In recent years, severe infections and even sepsis caused by adenovirus have shown a trend of periodic outbreaks. Early diagnosis of adenovirus-induced sepsis can not only prevent the overuse of broad-spectrum antibiotics but also ensure that patients receive timely and appropriate antiviral treatment. This article aims to provide a comprehensive review of the epidemiology, pathogenesis, diagnostic methods, and recent advances in treatment strategies for viral sepsis caused by adenovirus.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.