Evidence mapPaperPMID 40458607Full record

ReviewInternational journal of biomaterials2025

Protein-Based Silver Nanoparticles: Synthesis, Characterization, Administration, and Nanomedicine Applications.

Syed Muhammad Hasan, Saadat Hussain, Muhammad Yousuf, José Agustín Tapia-Hernández, Daim Asif Raja

Abstract readReview
In one paragraph

Review in International journal of biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Syed Muhammad HasanMemon Medical Institute Hospital, Karachi, Pakistan.ORCID https://orcid.org/0009-0001-9961-7371
Saadat HussainH.E.J Research Institute of Chemistry, ICCBS, University of Karachi, Karachi 75270, Pakistan.
Muhammad YousufDepartment of Biomedical and Biological Sciences, Sohail University, Karachi 74000, Pakistan.
José Agustín Tapia-HernándezDepartment of Food Research and Graduate Program, University of Sonora, C.P. 83000, Hermosillo, Sonora, Mexico.ORCID https://orcid.org/0000-0003-1124-7001
Daim Asif RajaH.E.J Research Institute of Chemistry, ICCBS, University of Karachi, Karachi 75270, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology has emerged as a transformative field in recent years, greatly impacting medicine and healthcare with innovative solutions for complex diseases. Among these advancements, protein-based metal nanoparticles have shown exceptional promise in treating chronic illnesses, owing to their high biocompatibility, biodegradability, customizable surface properties, and precise drug delivery capabilities. Recent studies have highlighted advancements in targeting efficiency and controlled release, alongside the ability of protein-based metal nanoparticles to bypass the first-pass metabolism, enhancing bioavailability through novel administration routes. Cutting-edge research has also focused on functionalizing protein nanostructures with therapeutic metal ions, particularly silver, with a longstanding antimicrobial and anti-inflammatory history. New combinations of silver with protein-based nanoparticles are now showing significant potential in managing chronic and life-threatening conditions. This review provides a comprehensive overview of the latest synthesis methods, toxicity assessments, therapeutic applications, administration pathways, and advanced characterization techniques for protein-based silver nanoparticles, addressing the evolving landscape of nanomedicine.

Indexed as

chronic diseasesnanomedicineprotein-based nanoparticlesroutes of administrationsilver

Identifiers

PMID40458607
PMCPMC12129617

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.