Evidence mapPaperPMID 40458765Full record

ArticleFrontiers in veterinary science2025

Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain body weight.

Hannah Godfrey, Érico de Mello Ribeiro, Shoshana Verton-Shaw, Anna Kate Shoveller, Darcia Kostiuk, Janelle Kelly, Jennifer Saunders Blades, Adronie Verbrugghe

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hannah GodfreyDepartment of Biomedical Sciences, University of Guelph, Guelph, ON, Canada.
Érico de Mello RibeiroDepartment of Clinical Studies, University of Guelph, Guelph, ON, Canada.
Shoshana Verton-ShawDepartment of Clinical Studies, University of Guelph, Guelph, ON, Canada.
Anna Kate ShovellerDepartment of Animal Biosciences, University of Guelph, Guelph, ON, Canada.
Darcia KostiukChampion Petfoods Holding Inc., Morinville, AB, Canada.
Janelle KellyChampion Petfoods Holding Inc., Morinville, AB, Canada.
Jennifer Saunders BladesChampion Petfoods Holding Inc., Morinville, AB, Canada.
Adronie VerbruggheDepartment of Clinical Studies, University of Guelph, Guelph, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: High consumption of dietary carbohydrates (nitrogen-free extract, NFE) in extruded dry foods is postulated as a risk factor for feline obesity, though evidence is limited. This study utilized a three-test diet approach to isolate the effect of each macronutrient on body composition, voluntary physical activity, and serum satiety hormone response in lean and obese cats. Materials and methods: A pairwise isoenergetic reduction as % metabolizable energy (ME, using modified Atwater) of dietary macronutrients created a low-protein (LP; protein = 28%, fat = 40%, NFE = 32%ME), low-fat (LF; protein = 40%, fat = 30%, NFE = 30%ME), and low-carbohydrate (LC; protein = 36%, fat = 41%, NFE = 23%ME) diet. Cats (lean Results: Greater lean soft tissue mass was observed for LF compared to LP and LC ( Discussion: Overall, the LP, LF, and LC diets were not associated with differences in most parameters, supporting that cats are metabolically flexible if nutrient requirements are met. There may be benefits regarding satiety hormone responses to a LC diet in cats though more research is required.

Indexed as

actigraphydietary carbohydratedietary fatdietary proteindual energy X-ray absorbsiometryfeline nutritionghrelinleptin

Identifiers

PMID40458765
PMCPMC12128646

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.