Evidence map›Paper›PMID 40459044›Full record

ArticleFaraday discussions2025

Spiers Memorial Lecture: Recent advances (and challenges) in supramolecular gels.

Haozhe Zheng, Darrin J Pochan

Abstract read
In one paragraph

Article in Faraday discussions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Haozhe ZhengDepartment of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA. pochan@udel.edu.ORCID http://orcid.org/0009-0001-7204-4817
Darrin J PochanDepartment of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA. pochan@udel.edu.ORCID http://orcid.org/0000-0002-0454-2339

Funding

Targeting mechanosignaling in pediatric brain cancerR01CA263216 · NCI · NEMOURS CHILDREN'S HOSPITAL, DELAWARE · PI Sigrid A Langhans · 2022 to 2026
$1.6M
NCI NIH HHS R01 CA263216
6 · The paper itself

Abstract

Supramolecular hydrogels are physical hydrogels that are formed by non-covalent interactions such as hydrogen bonding, electrostatic attraction, hydrophobic interactions, and π-π stacking. Compared to typical, chemically cross-linked hydrogels, supramolecular networks commonly have stimuli-responsive behavior including reversibility and injectability, which are being widely studied for uses in drug delivery, tissue engineering, and wound healing. This review highlights recent developments in supramolecular network design and behavior focusing on the different possible molecular building blocks, including peptides, polysaccharides, synthetic polymers, and multicomponent systems. We further discuss self-assembly mechanisms of hydrogel formation, as well as recent advances in stimuli-responsive supramolecular hydrogels triggered by pH, temperature, and light. Advanced characterization techniques such as rheological analysis, spectroscopy, scattering methods, and electron microscopy are summarized to understand hydrogel structure, assembly pathways, and ultimate network properties. This review provides readers with an updated understanding of supramolecular hydrogels and highlights current research presented during the

Identifiers

PMID40459044
PMCPMC12131310

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.