Evidence map›Paper›PMID 40460408›Full record

ArticleAmerican journal of respiratory cell and molecular biology2025

IL-33 Induces a Protective Response against Irritant-induced Airway Inflammation and Dysfunction.

Utako Fujii, Tomotaka Nishizawa, Yumiko Ishii, Emily Nakada, Kosuke Makita, Rui Sun, Toby McGovern, Arina Morozan, Rohin Chakraborty, James G Martin

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Regulating Neutrophilic Asthma with IL-33: Maybe We Shouldn't Block IL-33 after All?American journal of respiratory cell and molecular biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Utako FujiiMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
Tomotaka NishizawaMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
Yumiko IshiiMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
Emily NakadaMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
Kosuke MakitaMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
Rui SunMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
Toby McGovernMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
Arina MorozanMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
Rohin ChakrabortyMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.
James G MartinMeakins-Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and.ORCID 0000-0001-7574-5363

Funding

CIHR
6 · The paper itself

Abstract

IL-33 released by injurious stimuli to airway epithelium activates innate lymphoid cells (ILCs) that express IL-13. IL-33 and ILCs have an important role in type 2 (T2)-high asthma, but their influence on airway dysfunction induced by irritants is unclear. We examined the effects of Cl

Indexed as

InflammationInterleukin-33IrritantsAnimalsImmunity, InnateInterleukin-13LungLymphocytesMiceMice, Inbred BALB CMice, KnockoutIl33 protein, mouseInterleukin-13Interleukin-33IrritantsasthmaIL-10IL-13innate lymphoid cellsneutrophil

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.