Evidence map›Paper›PMID 40461640›Full record

ArticleThe EMBO journal2025

Sequence and parent-of-origin dependent m

Ying Zhang, Ze-Yu Zhang, Hong-Xuan Chen, Chao Liu, Biao-Di Liu, Ye-Lin Lan, Ying-Yuan Xie, Tao Chen, Shaobo Chen, Guihai Feng and 5 more

Abstract read
In one paragraph

Article in The EMBO journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ying Zhang *MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, China.ORCID http://orcid.org/0009-0006-6401-7938
Ze-Yu Zhang *Key Laboratory of Genetic Network Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.ORCID http://orcid.org/0000-0002-8352-0663
Hong-Xuan Chen *MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, China.
Chao LiuState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 100101, Beijing, China.
Biao-Di LiuMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, China.
Ye-Lin LanMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, China.
Ying-Yuan XieMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, China.
Tao ChenMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, China.
Shaobo ChenKey Laboratory of Genetic Network Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.
Guihai FengState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 100101, Beijing, China.
Zhang ZhangMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, China.
Wei LiState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 100101, Beijing, China.ORCID http://orcid.org/0000-0001-7864-404X
Nan CaoZhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, China.
Xiu-Jie WangKey Laboratory of Genetic Network Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.ORCID http://orcid.org/0000-0001-7865-0204
Guan-Zheng LuoMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, China. luogzh5@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-6797-9319

Funding

Ministry of Science and Technology of the People's Republic of China (MOST) 2022YFA0912900Ministry of Science and Technology of the People's Republic of China (MOST) 2022YFC3400400MOST | National Natural Science Foundation of China (NSFC) 32100461MOST | National Natural Science Foundation of China (NSFC) 32270644MOST | National Natural Science Foundation of China (NSFC) 32271499MOST | National Natural Science Foundation of China (NSFC) 32425034MOST | National Natural Science Foundation of China (NSFC) 92253202Pearl River Talent Recruitment Program 2019ZT08Y485
6 · The paper itself

Abstract

Multiple regulatory layers influence allele-specific expression (ASE), particularly through sequence-dependent and parent-of-origin-dependent mechanisms at the transcriptional level. However, little is known about ASE regulation at the post-transcriptional level. The most prevalent post-transcriptional mRNA modification, N

Indexed as

AdenosineAllelesGene Expression RegulationRNA Processing, Post-TranscriptionalAnimalsFemaleMaleMethylationMiceMice, Inbred C57BLAdenosineN-methyladenosineAllele-specific ExpressionCis Regulatory ElementGenomic Imprintingm6A ModificationParent-of-origin Effect

Identifiers

PMID40461640
PMCPMC12264043

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.