Evidence map›Paper›PMID 40462156›Full record

ArticleHereditas2025

The bibliometric analysis of research on traditional Chinese medicine regulating gut microbiota for cancer treatment from 2014 to 2024.

Youfeng Lei, Yueqin Shan, Danfeng Zhou, Chunyan Chen

Abstract read
In one paragraph

Article in Hereditas, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Youfeng Lei *Department of Pharmacy, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yueqin Shan *Department of Pharmacy, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Danfeng ZhouDepartment of Pharmacy, Jinshan Hospital of Fudan University, Shanghai, China.
Chunyan ChenDepartment of Pharmacy, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China. chenchunyan@shaphc.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe modulation of gut microbiota by Traditional Chinese Medicine (TCM) offers a promising approach to cancer treatment. However, a comprehensive bibliometric evaluation of this emerging field is lacking.

objectiveThis study aimed to systematically analyze global research trends, hotspots, and future directions related to TCM regulation of gut microbiota in cancer therapy from 2014 to 2024.

methodsPublications were retrieved from the Web of Science Core Collection. Bibliometric and visual analyses were conducted using VOSviewer and CiteSpace to examine publication trends, country and institutional collaborations, core authors and journals, keyword co-occurrence, and research frontiers.

resultsA total of 340 relevant articles were identified. The number of publications increased significantly after 2018, indicating growing interest in this field. China dominated the research landscape, both in productivity and institutional collaboration. Core research hotspots included "short-chain fatty acids," "tumor microenvironment," "apoptosis," and "immune response." Thematic evolution analysis highlighted a shift from general gut microbiota research to precise molecular mechanisms and targeted regulation. Emerging topics such as "metabolomics" and "immune checkpoint blockade" suggest future directions.

conclusionThis study provides a comprehensive overview of the current research landscape on TCM-modulated gut microbiota in cancer treatment. By identifying core contributors, research hotspots, and frontiers, it offers valuable guidance for future investigations and interdisciplinary collaborations in this promising field.

Indexed as

BibliometricsGastrointestinal MicrobiomeMedicine, Chinese TraditionalNeoplasmsHumansBibliometricCancerCancer treatmentGut microbiotaTraditional Chinese medicine

Identifiers

PMID40462156
PMCPMC12131599

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.