Evidence map›Paper›PMID 40463175›Full record

ArticlebioRxiv : the preprint server for biology2025

Basolateral amygdala dopamine transmits a nonassociative emotional salience signal.

Megan A Brickner, William E Szot, Amy R Wolff, Mark J Thomas, Benjamin T Saunders

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Megan A BricknerDepartment of Neuroscience, University of Minnesota.ORCID 0000-0002-3020-718X
William E SzotDepartment of Neuroscience, University of Minnesota.
Amy R WolffDepartment of Neuroscience, University of Minnesota.
Mark J ThomasDepartment of Neuroscience, University of Minnesota.
Benjamin T SaundersDepartment of Neuroscience, University of Minnesota.ORCID 0000-0002-4733-1101

Funding

Viral Innovation CoreP30DA048742 · NIDA · UNIVERSITY OF MINNESOTA · PI TIMOTHY J EBNER · 2020 to 2026
$19.0M
Functional architecture of striatal networks in cue-reward learningR01MH129370 · NIMH · UNIVERSITY OF MINNESOTA · PI Benjamin Thomas Saunders · 2023 to 2026
$2.4M
Circuit-level neurodevelopmental trajectories of decision-making computations across adolescenceR01MH129320 · NIMH · UNIVERSITY OF MINNESOTA · PI GROMAN, STEPHANIE MARY, SAUNDERS, BENJAMIN THOMAS · 2022 to 2024
$2.1M
Basolateral amygdala dopamine in addiction-related learning strategiesR01DA057292 · NIDA · UNIVERSITY OF MINNESOTA · PI Benjamin Thomas Saunders · 2024 to 2026
$1.2M
Midbrain cellular and circuit dynamics of cocaine seekingR00DA042895 · NIDA · UNIVERSITY OF MINNESOTA · PI SAUNDERS, BENJAMIN THOMAS · 2018 to 2020
$747k
Characterizing BLA dopaminergic and glutamatergic mechanisms of dynamic drug seekingF31DA060004 · NIDA · UNIVERSITY OF MINNESOTA · PI Megan A Brickner · 2024 to 2026
$145k
NIDA NIH HHS F31 DA060004NIDA NIH HHS P30 DA048742NIDA NIH HHS R00 DA042895NIDA NIH HHS R01 DA057292NIMH NIH HHS R01 MH129320NIMH NIH HHS R01 MH129370
6 · The paper itself

Abstract

Adaptive decision making relies on proper discrimination and prediction of positive and negative events. The basolateral amygdala (BLA) is central to this valence encoding, assigning emotional value to stimuli to drive appropriate behavioral responses. The ventral tegmental area (VTA), which is classically known to regulate associative learning and incentive motivation via dopamine projections to the striatum, also contains strong dopamine projections to the BLA, but this system has received much less attention. Here, we investigated how

Identifiers

PMID40463175
PMCPMC12132325

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.