Evidence map›Paper›PMID 40463288›Full record

ArticlebioRxiv : the preprint server for biology2025

Roles of the MO25 protein Pmo25 in contractile-ring stability and localization of the NDR kinase Sid2 during cytokinesis.

Yanfang Ye, Sha Zhang, Jack R Gregory, Aysha H Osmani, Evelyn G Goodyear, Jian-Qiu Wu

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yanfang YeDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.
Sha ZhangDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.
Jack R GregoryDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.ORCID 0009-0009-3715-8710
Aysha H OsmaniDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.
Evelyn G GoodyearDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.
Jian-Qiu WuDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-5088-0769

Funding

Molecular Mechanisms of CytokinesisR01GM118746 · NIGMS · OHIO STATE UNIVERSITY · PI WU, JIAN-QIU · 2016 to 2025
$2.7M
Cellular, molecular, and biochemical sciences training grantT32GM141955 · NIGMS · OHIO STATE UNIVERSITY · PI Jane Elizabeth Jackman, JESSE J KWIEK · 2021 to 2026
$2.2M
NIGMS NIH HHS R01 GM118746NIGMS NIH HHS T32 GM141955
6 · The paper itself

Abstract

Mouse protein-25 (MO25) family proteins are crucial in development and morphogenesis from plants to humans. The fission yeast MO25 protein Pmo25 is essential for cell polarity and division. However, how Pmo25 regulates cytokinesis remains largely unknown. Here we found that the actomyosin contractile ring and septum formation were defective during cytokinesis in

Indexed as

Cdc4contractile ringcytokinesisglucanase Eng1MO25Munc13/UNC-13septumSid2SIN pathwayYnc13

Identifiers

PMID40463288
PMCPMC12132425

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.