Evidence mapPaperPMID 40463443Full record

SynthesisFrontiers in microbiology2025

Exploring the research progression and evolutionary trends of gut microbiome and hypertension: a bibliometric analysis.

Xinyu Huang, Yingying Liu, Feng Jiang, Laiyun Xin, Zhenyuan Wang, Zhen Hua, Cong Wang, Lei Zhang, Jie Yu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinyu HuangThe First Clinical Medical College of Shandong University of Traditional Chinese Medicine, Shandong, China.
Yingying LiuThe Third Department of Cardiovascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.
Feng JiangThe Third Department of Cardiovascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.
Laiyun XinThe Third Department of Cardiovascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.
Zhenyuan WangThe Third Department of Cardiovascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.
Zhen HuaThe Third Department of Cardiovascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.
Cong WangThe Third Department of Cardiovascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.
Lei ZhangThe Third Department of Cardiovascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.
Jie YuThe Third Department of Cardiovascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is one of the most common cardiovascular diseases, with multiple underlying mechanisms. The gut microbiome, as one of the most important microbial communities in the human body, plays a significant role in the development of various diseases, including hypertension. While numerous studies have explored the relationship between gut microbiome and hypertension from different perspectives, there has been no bibliometric study in this field. Therefore, a bibliometric analysis is crucial for accurately assessing and summarizing the current research status. The analysis indicates that the number of publications in this field has steadily increased in recent years, with China and the United States leading in development. The journal Nutrients has the highest number of published papers, and Marques, Francine Z is a prominent figure with significant contributions and influence in this field. Co-occurrence and trend analysis suggest that the main research hotspots include the relationship between gut microbiome and hypertension, mechanisms by which gut microbiome promotes hypertension, and new therapeutic strategies targeting gut microbiome to improve hypertension. Future research trends may focus on expanding new metabolites or measurement techniques, building databases of human and animal gut microbiota and their metabolites, and developing new drugs targeting gut microbiota for hypertension. In summary, this study visually demonstrates the dynamic changes in research hotspots, revealing new patterns and focuses in the field, and aims to provide new insights for clinical work on hypertension.

Indexed as

bibliometric analysisCiteSpacegut microbiomehypertensionresearch progressionVOSviewer

Identifiers

PMID40463443
PMCPMC12130031

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.