ReviewFrontiers in nutrition2025
The neurobiology of plant-based therapeutics in women's reproductive health: mechanisms, efficacy, and clinical translation.
Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Plant Flavonoid-Enriched Functional Foods for Polycystic Ovary Syndrome: Dietary Sources, Bioavailability Enhancement, and Personalized Intervention Strategies.Food science & nutrition · 2026Review
- Dual action of herbal compounds inFrontiers in immunology · 2026Review
- Flavonoids: biological activities, nutritional and immunological aspects, therapeutic potential, food applications, and human health benefits-A comprehensive review.Frontiers in nutrition · 2026Review
- Integrated Network Toxicology and Metabolomics Reveal the Ovarian Toxicity Mechanisms of Chronic Carbofuran Exposure in Female Mice.International journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review examines the neurobiological mechanisms by which plant-derived compounds influence women's reproductive health through the neuroendocrine-reproductive axis. Gynecological disorders frequently present with neurological manifestations, including cognitive decline in perimenopause, anxiety and depression in polycystic ovary syndrome (PCOS), and central sensitization in endometriosis. Bioactive compounds from medicinal plants, including polyphenols and phytoestrogens, demonstrate therapeutic potential through their anti-inflammatory, antioxidant, and neuromodulatory properties. These multi-target compounds offer advantages over conventional single-target therapies by simultaneously regulating multiple physiological processes. The review explores applications in specific gynecological conditions and discusses the development of dietary supplements and functional foods incorporating these plant-derived ingredients. The growing market for these products presents opportunities for innovative formulations with enhanced bioavailability and personalized approaches. Future research directions include integrating neuroimaging with herbal research, improving clinical translation, and establishing regulatory frameworks for the global application of these plant-derived interventions to enhance female neuroendocrine-reproductive health.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.