ArticleJournal of conservative dentistry and endodontics2025
Antibacterial efficacy of herbal extracts as photosensitizers in photodynamic root canal disinfection.
Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Sample size calculation practices in original research articles of the Journal of Conservative Dentistry and Endodontics (2021-2025).Journal of clinical and experimental dentistry · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Context: Photodynamic root canal disinfection is a valuable adjunct in endodontics. However, the standard photosensitizer often causes tooth discoloration. Natural photosensitizers, such as curcumin (CUR) and Aims: This study evaluates the antibacterial effectiveness of BV extract as a photosensitizer in antimicrobial photodynamic therapy (aPDT) against Settings and Design: A comprehensive study protocol outlining the objectives and methodologies was submitted to the Institutional Ethics Committee and received ethical approval (Approval No. 2024-25/1114). Subjects and Methods: Fifty-six single-rooted extracted teeth were prepared using Protaper Gold to #F3, irrigated with 3% sodium hypochlorite (NaOCl), and finalized with 17% ethylenediaminetetraacetic acid. The teeth were contaminated with Statistical Analysis Used: Data were subjected to statistical analysis using SPSS v22, with analysis of variance and Results: NaOCl combined with CUR-PDT showed the highest CFU reduction, followed by NaOCl with TB and BV. Nonphotoactivated photosensitizers were less effective in comparison. Conclusions: Photoactivated CUR and BV extracts demonstrated superior antimicrobial activity compared to their nonphotoactivated forms, suggesting their potential as alternative photosensitizers in aPDT.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.