Evidence map›Paper›PMID 40464570›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025

Precision and Accuracy of Dimensional Assessment of Luminal Contours by Commercially Available Quantitative Angiography Software as a Prerequisite to Angiography Based FFR and Other Derived Parametrics.

Akihiro Tobe, Kotaro Miyashita, Pruthvi C Revaiah, Tsung-Ying Tsai, Asahi Oshima, Shiuan Hao Hu, Emelyne Sevestre, Scot Garg, Christos Bourantas, Chrysafios Girasis and 3 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Akihiro TobeCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Kotaro MiyashitaCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Pruthvi C RevaiahCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Tsung-Ying TsaiCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Asahi OshimaCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Shiuan Hao HuCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Emelyne SevestreCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Scot GargDepartment of Cardiology, Royal Blackburn Hospital, Blackburn, UK.
Christos BourantasDepartment of Cardiology, Barts Heart Center, Barts Health NHS Trust, London, UK.
Chrysafios GirasisEUROMEDICA General Clinic of Thessaloniki, Thessaloniki, Greece.
Jolanda J WentzelDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Yoshinobu OnumaCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Patrick W SerruysCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.ORCID https://orcid.org/0000-0002-9636-1104

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundAccurate dimensional measurements are critical for quantitative coronary angiography (QCA) and serve as the first step in angiography-based fractional flow reserve (FFR) calculations.

aimsTo compare minimum lumen diameter (MLD) measurements across multiple QCA or anigo-based FFR software programs using phantom models.

methodsFourteen QCA and angio-based FFR programs were evaluated using six plexiglass phantoms, each containing three sequential bifurcations with known true values for the MLD of the proximal main, distal main, and side branch vessels. The accuracy and precision of MLD measurements were assessed by comparing software-measured values with true values across 54 MLD measurement points. No manual correction of the vessel contour was performed. The results of the 14 programs were reported anonymously.

resultsThe mean differences between the measured and true values were small (< 0.1 mm), however, in two angio-based FFR programs, the discrepancies were large (> 0.3 mm). The standard deviations of the differences were approximately 0.1 mm, except in one angio-based FFR program, where it exceeded 0.3 mm. Differences from true values were more pronounced in small (≦ 0.7 mm) compared to large (> 0.7 mm) true MLDs. The reproducibility of measurements was high (Pearson's correlation coefficient > 0.98) across all programs.

conclusionVariations in MLD measurements were observed among different QCA and angio-based FFR programs. These variations may influence diagnostic performance and can seriously impact decisions made solely using angio-based FFR.

Indexed as

Coronary AngiographyCoronary Artery DiseaseCoronary VesselsFractional Flow Reserve, MyocardialRadiographic Image Interpretation, Computer-AssistedSoftwareHumansModels, CardiovascularPhantoms, ImagingPredictive Value of TestsReproducibility of Results

Identifiers

PMID40464570
PMCPMC12336765

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.