Evidence mapPaperPMID 40464697Full record

ReviewTransactions of the Royal Society of Tropical Medicine and Hygiene2025

Decoding leprosy: immune response, clinical manifestations and emerging diagnostic approaches.

Héctor Serrano-Coll, Lina Restrepo-Rivera, Yicenia Cuadros-Urrego, Nora Cardona-Castro

Abstract readReview
In one paragraph

Review in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Héctor Serrano-CollLeprosy research group, Instituto Colombiano de Medicina Tropical-Universidad CES, Medellín 050001, Colombia.ORCID 0000-0002-8872-872X
Lina Restrepo-RiveraLeprosy research group, Instituto Colombiano de Medicina Tropical-Universidad CES, Medellín 050001, Colombia.ORCID 0000-0002-0439-9691
Yicenia Cuadros-UrregoLeprosy research group, Instituto Colombiano de Medicina Tropical-Universidad CES, Medellín 050001, Colombia.
Nora Cardona-CastroLeprosy research group, Instituto Colombiano de Medicina Tropical-Universidad CES, Medellín 050001, Colombia.ORCID 0000-0002-4716-6636

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leprosy is an infectious disease characterized by a broad immunological spectrum, which underlies its diverse clinical presentations and contributes to the physical and emotional disabilities experienced by patients with leprosy. Understanding the immunopathogenic mechanisms of this disease is essential for interpreting clinical manifestations and conventional diagnostic tests and developing diagnostic strategies for leprosy detection. This review aims to provide an overview of the immune response, clinical features and emerging diagnostic approaches in leprosy.

Indexed as

LeprosyMycobacterium lepraeHumansdisabilityearly detectionimmunologyleprosyneglected diseasepathology

Identifiers

PMID40464697
PMCPMC12403208

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.