Evidence map›Paper›PMID 40464781›Full record

ArticleBiological research for nursing2025

Pain Resilience and Chronic Low Back Pain Outcomes: The Mediating Role of Pace of Biological Aging.

Kiari Kinnie Davis, Khalid W Freij, Fiona B A T Agbor, Asia M Wiggins, Tammie L Quinn, Demario S Overstreet, Shivraj S Grewal, Robert E Sorge, Burel R Goodin, Edwin N Aroke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biological research for nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kiari Kinnie DavisDepartment of Acute, Chronic and Continuing Care, School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0009-0001-5696-1674
Khalid W FreijDepartment of Acute, Chronic and Continuing Care, School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0009-0001-1795-2927
Fiona B A T AgborDepartment of Acute, Chronic and Continuing Care, School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0009-0006-9169-5064
Asia M WigginsDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Tammie L QuinnDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Demario S OverstreetDepartment of Surgery, UAB Heersink School of Medicine, Birmingham, AL, USA.ORCID 0000-0002-8485-4454
Shivraj S GrewalDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Robert E SorgeDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Burel R GoodinDepartment of Anesthesiology, School of Medicine, Washington University, St Louis, MO, USA.
Edwin N ArokeDepartment of Acute, Chronic and Continuing Care, School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-8355-0870

Funding

NIMHD NIH HHS R01 MD010441
6 · The paper itself

Abstract

In this study, we aimed to investigate if the pace of biological aging serves as a critical mediator in the relationship between chronic pain resilience and chronic low back pain intensity and disability. Two hundred seven community-dwelling non-Hispanic Black (NHB) and non-Hispanic White (NHW) adults completed the Pain Resilience Scale (PRS) and Graded Chronic Pain Scale (GCPS). Blood genomic DNA was sequenced using Illumina's MethylationEPIC, and the pace of biological aging estimated using the DunedinPACE (the Dunedin Pace of Aging Calculated from the Epigenome) algorithm. In bivariate correlations, DunedinPACE significantly correlated with pain intensity (r = 0.40), and disability (r = 0.39), at

Indexed as

AgingChronic PainLow Back PainResilience, PsychologicalAdultAgedBlack or African AmericanFemaleHumansMaleMiddle AgedPain MeasurementWhitechronic low back painDNA methylationdunedinpaceepigenetic agingmediationresilience

Identifiers

PMID40464781
PMCPMC12605910

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.