Evidence map›Paper›PMID 40467474›Full record

ReviewEndocrine journal2025

Ectopic production of 1,25-dihydroxyvitamin D in high-grade intranasal non-intestinal-type adenocarcinoma induced hypercalcemic crisis: a case report with review of literature.

Muneo Kawasumi, Mitsunobu Kubota, Hiromi Furuie, Kazuya Kuraoka

Abstract readCase ReportsReview
In one paragraph

Review in Endocrine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muneo KawasumiDepartment of Endocrinology and Diabetology, Hiroshima City North Medical Center Asa Citizens Hospital, Hiroshima 731-0293, Japan.ORCID http://orcid.org/0000-0001-7864-7785
Mitsunobu KubotaDepartment of Endocrinology and Diabetology, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Hiroshima 737-0023, Japan.ORCID http://orcid.org/0000-0001-8562-5939
Hiromi FuruieDepartment of Otorhinolaryngology, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Hiroshima 737-0023, Japan.
Kazuya KuraokaDepartment of Diagnostic Pathology, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Hiroshima 737-0023, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypercalcemia is an oncologic metabolic emergency in cancer patients, primarily caused by local osteolytic hypercalcemia and humoral hypercalcemia of malignancy. Hormones associated with oncologic metabolic emergency include parathyroid hormone and parathyroid hormone-related peptide (PTHrP), but 1,25-dihydroxyvitamin D (1,25(OH)

Indexed as

AdenocarcinomaHypercalcemiaNose NeoplasmsVitamin D25-Hydroxyvitamin D3 1-alpha-HydroxylaseAged, 80 and overHumansMaleVitamin D3 24-Hydroxylase1,25-dihydroxyvitamin D25-Hydroxyvitamin D3 1-alpha-HydroxylaseCYP24A1 protein, humanCYP27B1 protein, humanVitamin DVitamin D3 24-Hydroxylase1,25-Dihydroxyvitamin D (1,25(OH)2D)CYP27B1Ectopic expressionHigh-grade intranasal non-intestinal-type adenocarcinoma (non-ITAC)Hypercalcemic crisis

Identifiers

PMID40467474
PMCPMC12510782

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.