Evidence map›Paper›PMID 40468767›Full record

ArticleJournal of materials chemistry. B2025

Charge engineering controls cooperative assembly and loading in protein host-guest complexes.

Zhiheng Wang, Dai-Bei Yang, Joshua A Bulos, Rui Guo, Thomas Troxler, Sergei Vinogradov, Jeffery G Saven, Ivan J Dmochowski

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of materials chemistry. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Cavity acidification limits ferritin iron biomineralization.Journal of inorganic biochemistry · 2026
    Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Zhiheng WangDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, USA. ivandmo@sas.upenn.edu.
Dai-Bei YangDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, USA. ivandmo@sas.upenn.edu.ORCID http://orcid.org/0009-0009-3327-6920
Joshua A BulosDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, USA. ivandmo@sas.upenn.edu.
Rui GuoDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, USA. ivandmo@sas.upenn.edu.
Thomas TroxlerDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, USA. ivandmo@sas.upenn.edu.
Sergei VinogradovDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, USA. ivandmo@sas.upenn.edu.ORCID http://orcid.org/0000-0002-4649-5534
Jeffery G SavenDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, USA. ivandmo@sas.upenn.edu.ORCID http://orcid.org/0000-0001-5027-7241
Ivan J DmochowskiDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, USA. ivandmo@sas.upenn.edu.ORCID http://orcid.org/0000-0001-7162-1347

Funding

Designer Molecular Probes for Biomedical ApplicationsR35GM131907 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Ivan Julian Dmochowski · 2019 to 2026
$4.7M
NIGMS NIH HHS R35 GM131907
6 · The paper itself

Abstract

Controlling cargo loading in self-assembling protein capsules remains a key challenge in supramolecular chemistry. Inspired by nature's capacity for host-guest recognition, we engineered supercharged green fluorescent protein (GFP) cargo for controlling its encapsulation by

Indexed as

FerritinsGreen Fluorescent ProteinsProtein EngineeringArchaeoglobus fulgidusMolecular Dynamics SimulationFerritinsGreen Fluorescent Proteins

Identifiers

PMID40468767
PMCPMC12884264

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.