Evidence map›Paper›PMID 40469607›Full record

ArticleFrontiers in public health2025

Risk factors and traditional Chinese medicine syndromes of mild cognitive impairment in community-dwelling hypertensive older adults.

Jie Gao, Meirong Wu, Siyuan Jia, Yuan Tian, Dengkun Wang, Xiaojing Lei, Yongchang Diwu

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie Gao *The First Clinical College of Medicine, Shaanxi University of Chinese Medicine, Xianyang, China.
Meirong WuThe First Clinical College of Medicine, Shaanxi University of Chinese Medicine, Xianyang, China.
Siyuan JiaThe First Clinical College of Medicine, Shaanxi University of Chinese Medicine, Xianyang, China.
Yuan TianThe First Clinical College of Medicine, Shaanxi University of Chinese Medicine, Xianyang, China.
Dengkun WangAffiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, China.
Xiaojing LeiCollege of Basic Medicine, Shaanxi University of Chinese Medicine, Xianyang, China.
Yongchang Diwu *College of Basic Medicine, Shaanxi University of Chinese Medicine, Xianyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypertension is recognized as a risk factor for cognitive impairment in older adults. This study aimed to investigate the prevalence, associated factors, and traditional Chinese medicine (TCM) syndrome elements of mild cognitive impairment (MCI) among hypertensive older adults within Chinese communities. Methods: A community-based cross-sectional study was conducted involving hypertensive individuals. Participants were diagnosed with hypertension through medical history and physical examination, and were assessed for MCI using neuropsychological scales. TCM syndrome elements were evaluated using the Dementia Syndrome Scale. Logistic regression analysis was employed to identify risk factors for MCI and associated TCM syndromes. Results: The prevalence of MCI among 715 hypertensive participants was found to be 35.4%. Multivariate logistic regression analysis revealed sleep disorders as a significant risk factor for MCI (OR = 3.855, 95% CI: 2.454-6.055). Conversely, a higher education level, mental work, antihypertensive medication, and healthy lifestyle habits-including frequent tea consumption, reading, social interaction, and daily exercise-were identified as protective factors against MCI. TCM syndrome analysis indicated that marrow-deficiency, internal-heat, and phlegm-turbidity were significantly associated with an increased risk of MCI. Conclusion: The prevalence of MCI is high among older adults hypertensive individuals in Chinese communities, influenced by a combination of risk and protective factors. Sleep disorders represent a major risk factor, while modifiable lifestyle and medical factors serve as protective elements. Marrow-deficiency, internal-heat, and phlegm-turbidity are key TCM syndrome elements related to MCI. These findings underscore the importance of dynamic cognitive assessment in hypertensive patients and suggest personalized interventions that integrate both Western and TCM approaches for the prevention and management of MCI.

Indexed as

Cognitive DysfunctionHypertensionIndependent LivingMedicine, Chinese TraditionalAgedAged, 80 and overChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedNeuropsychological TestsPrevalenceRisk FactorsSyndromecommunityhypertensioninfluencing factorsmild cognitive impairmentolder adultstraditional Chinese medicine syndrome elements

Identifiers

PMID40469607
PMCPMC12133820

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.