ArticleFrontiers in medicine2025
Establishment of reference intervals for complete blood count in healthy adults at different altitudes on the Western Sichuan Plateau.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Establishing population-based reference intervals for hematological parameters among apparently healthy adults in Northwest Ethiopia, 2023.Scientific reports · 2026Article
- Commentary: Establishment of reference intervals for complete blood count in healthy adults at different altitudes on the Western Sichuan Plateau.Frontiers in medicine · 2025Article
- Application of machine learning to predict the occurrence of venous thromboembolism in patients hospitalized for coronary artery disease: a single-center retrospective study.Frontiers in cardiovascular medicine · 2025Article
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11 authors.
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Abstract
Background: A detailed reference range for complete blood count of healthy adults in the Western Sichuan Plateau region is unavailable. This study aimed to explore changes in complete blood count (CBC) in healthy adults across high-altitude regions of Ganzi Prefecture, Sichuan Province, to establish altitude-specific reference intervals and improve diagnostic accuracy and provide tailored clinical guidance for residents in these areas. Methods: CBC data from 3,485 healthy individuals from four altitudes-Guza (1,400 m), Lucheng (2,500 m), Luhuo (3,200 m), and Litang (4,100 m)-were collected between January 2022 and December 2023. The data were analyzed by sex, altitude, age groups, and their interactions to establish reference intervals. Results: CBC indicators showed significant changes with increasing altitude. Red blood cell (RBC) count, hemoglobin (HGB), hematocrit (HCT), white blood cell (WBC) count, and platelet (PLT) count all significantly increased as altitude rose ( Conclusion: This study established CBC reference intervals for the high-altitude regions of Ganzi Prefecture, revealing significant variations by altitude, sex, and age. These findings provide valuable insights for improving disease diagnosis and medical care for high-altitude residents.
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