Evidence mapPaperPMID 40470262Full record

ReviewFrontiers in cellular and infection microbiology2025

Prostate and urinary microbiomes in prostate cancer development: focus on

Fangzhi Fu, Yunfeng Yu, Biao Wang, Xiang Zhao, Neng Wang, Jubo Yin, Kai Wu, Qing Zhou

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Genetic Polymorphisms and Antioxidant Reactions in Prostate Cancer.International journal of molecular sciences · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fangzhi FuDepartment of Andrology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Yunfeng YuDepartment of Andrology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Biao WangDepartment of Andrology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Xiang ZhaoDepartment of Andrology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Neng WangDepartment of Andrology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Jubo YinDepartment of Andrology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Kai WuDepartment of Andrology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Qing ZhouDepartment of Andrology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is one of the most prevalent malignancies among men, with its incidence steadily increasing worldwide. Recent advances in microbiome research have opened new avenues for understanding and treating PCa; however, studies focusing specifically on the prostate tissue microbiome remain limited. Evidence suggests that the microbial communities within PCa tissues exhibit significant diversity and regional variability, with certain bacteria potentially contributing to PCa initiation and progression through chronic inflammation. The prostate microbiome comprises not only bacteria but also viruses, fungi, and parasites, and its diversity is influenced by a complex interplay of genetic, environmental, and lifestyle factors. Methodological limitations and sample contamination further complicate the interpretation of microbiome data. The urinary microbiome is similarly diverse and shaped by multiple overlapping influences. Although urine, prostatic fluid, and prostate tissue are anatomically and functionally connected, whether urine and prostatic fluid can accurately reflect the prostate tissue microbiome remains to be conclusively determined. Among the microorganisms detected,

Indexed as

MicrobiotaPropionibacteriaceaeProstateProstatic NeoplasmsUrineHumansMalebacteriaCutibacterium acnesmicrobiomeprostate cancerurine

Identifiers

PMID40470262
PMCPMC12133773

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.