Evidence map›Paper›PMID 40470490›Full record

SynthesisFrontiers in neurology2025

The effect of exercise intervention on amyotrophic lateral sclerosis: a systematic review and meta-analysis.

Shuangquan Ren, Xinrui Che, Shunding Hu, Xiaosu Feng, Jianming Zhang, Peng Shi

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuangquan RenNortheast Petroleum University, Daqing, China.
Xinrui CheLiaoning Police College, Dalian, China.
Shunding HuSchool of Physical Education, Liaoning Normal University, Dalian, China.
Xiaosu FengSchool of Physical Education, Liaoning Normal University, Dalian, China.
Jianming ZhangSchool of Physical Education, Liaoning Normal University, Dalian, China.
Peng ShiSchool of Physical Education, Shandong University of Technology, Zibo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Quantitative evaluation of the effect of exercise intervention in amyotrophic lateral sclerosis (ALS). Methods: The CNKI, WOS, PubMed, and Scopus databases were searched by computer, and randomized controlled trials (RCTs) of exercise intervention in ALS were screened out according to the inclusion and exclusion criteria of the PICOS principle. Stata 12.0 software was used for statistical analysis. Results: A total of 12 RCTs including 430 participants were included. Meta-analysis results show that exercise intervention can significantly improve the overall function, walking test (WT) distance and maximum expiratory pressure (MEP) of ALS patients ( Conclusion: Exercise intervention in ALS has a positive effect, but due to the small number of included studies and possible heterogeneity, risk of bias and sensitivity issues, further research is needed.

Indexed as

amyotrophic lateral sclerosisexercisemeta-analysisphysical functionrespiratory function

Identifiers

PMID40470490
PMCPMC12133518

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.