Evidence map›Paper›PMID 40473459›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Quantitative [

Ameer Mansur, Jonathan E McConathy, Erica Stringer-Reasor, Gabrielle Rocque, Katia Khoury, Noon Eltoum, Moozhan Nikpanah, Jennifer Bartels, Brian Wright, Nusrat Jahan and 3 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. EJNMMI research · 2026
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ameer MansurDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama.
Jonathan E McConathyO'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, Alabama.
Erica Stringer-ReasorO'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, Alabama.
Gabrielle RocqueDivision of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, Alabama; and.
Katia KhouryDivision of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, Alabama; and.
Noon EltoumDepartment of Radiology, University of Alabama, Birmingham, Alabama.
Moozhan NikpanahDepartment of Radiology, University of Alabama, Birmingham, Alabama.
Jennifer BartelsDepartment of Radiology, University of Alabama, Birmingham, Alabama.
Brian WrightDepartment of Radiology, University of Alabama, Birmingham, Alabama.
Nusrat JahanDivision of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, Alabama; and.
Denise JeffersDepartment of Radiology, University of Alabama, Birmingham, Alabama.
Suzanne E LapiO'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, Alabama; agsorace@uab.edu lapi@uab.edu.
Anna G SoraceDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama; agsorace@uab.edu lapi@uab.edu.

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
NCI NIH HHS P30 CA013148
6 · The paper itself

Abstract

Current methods for evaluating HER2 expression in breast cancer are invasive and fail to capture spatial and temporal heterogeneity between primary tumors and metastases. Nuclear imaging allows for whole-body, noninvasive assessment of human epidermal growth factor receptor 2 (HER2) and can distinguish between HER2-positive and HER2-negative lesions. MRI offers superior soft-tissue contrast and quantitative metrics, such as the apparent diffusion coefficient (ADC) from diffusion-weighted (DW) imaging, providing prognostic value. The goal of this study was to present quantitative imaging metrics from [

Indexed as

Breast NeoplasmsDiffusion Magnetic Resonance ImagingErb-b2 Receptor Tyrosine KinasesPositron-Emission TomographyTrastuzumabZirconiumAdultAgedAntibodies, Monoclonal, HumanizedFemaleHumansMiddle AgedMultimodal ImagingNeoplasm MetastasisRadioisotopesAntibodies, Monoclonal, HumanizedERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesRadioisotopesTrastuzumabZirconiumzirconium-89-trastuzumab[89Zr]Zr-trastuzumabDW-MRIHER2 PET/MRIHER2-positive metastatic breast cancermultiparametric

Identifiers

PMID40473459
PMCPMC12212413

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.