ArticleeNeuro2025
Functional Connectome Correlates of Laterality Preferences: Insights into Hand, Foot, and Eye Dominance across the Lifespan.
Article in eNeuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Humans exhibit laterality preferences, with handedness being the most extensively studied. Accordingly, brain-handedness associations are well documented. However, laterality preferences extend beyond handedness to include other limbs, such as footedness and eyedness. Despite these distinctions, brain-footedness and brain-eyedness associations using resting-state functional connectomes remain largely unexplored. We utilize two large datasets, the Human Connectome Project-Development (HCP-D) and Human Connectome Project-Aging (HCP-A), to study the associations between sidedness (i.e., handedness, footedness, and eyedness) and whole-brain functional connectomes. While hand and foot preferences were correlated significantly, they explained <40% of the variance, suggesting some distinctions between measures. For both cohorts, significant associations between handedness connectivity were observed [
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