ReviewNature reviews. Disease primers2025
Placenta accreta spectrum.
Review in Nature reviews. Disease primers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Uterovesical tourniquet for conservative management of placenta accreta spectrum: a prospective cohort study in a low-resource setting.BMC pregnancy and childbirth · 2025Trial
- The Role of Interventional Radiology in the Diagnosis and Treatment of Gynecological Conditions.Tomography (Ann Arbor, Mich.) · 2026Review
- Spatial Logic and Evolutionary Innovation in Human Placentation.bioRxiv : the preprint server for biology · 2026Article
- Maternal serum thrombospondin-4 levels in placenta accreta spectrum: A case-control study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Placenta Praevia and Placenta Accreta Spectrum: Diagnosis and Management: Green-Top Guideline No. 27a.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Placental basal plate with attached myofibers and adverse pregnancy outcomes: A systematic scoping review.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Towards precision medicine in placenta accreta spectrum: results from a survey-based evaluation of interactive academic international webinars.BMC pregnancy and childbirth · 2026Article
- Evaluation of the role of post-partum ultrasound of cesarean delivery scar on subsequent pregnancy outcomes: a preliminary study.BMC pregnancy and childbirth · 2026Article
- KRT6A Is a Biomarker of PAS Progression and Enhances the Invasive Ability of Trophoblast Cells.Cells · 2026Article
- Placenta accreta spectrum in the 21st century: Challenging dogma and redefining disorder.PLoS medicine · 2026Article
- The diagnostic value of multiple schemes of MRI standard features combined with risk factors and ultrasound for Placenta accreta spectrum.BMC pregnancy and childbirth · 2026Article
- Risk factors for partial placental retention after Cesarean delivery: a preliminary report.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026Article
- Multidisciplinary team approach in placenta accreta surgery: concerns and clarifications.Archives of gynecology and obstetrics · 2026Article
- Conservative management of placenta accreta spectrum disorders: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- 3D imaging of the pregnant uterus reveals an extensively invasive mouse placenta and early CXCL12-CXCR4 requirement.bioRxiv : the preprint server for biology · 2026Article
- Successful conservative management of placenta accreta spectrum in Ethiopia: a case report and literature review.BMC pregnancy and childbirth · 2026Review
- Evaluation of the role of the rail sign and intracervical lakes in the management of patients with a high probability of placenta accreta spectrum.BMC pregnancy and childbirth · 2026Article
- Cesarean Scar Implantation in the Evolution of Placenta Accreta Spectrum: Implications for Recognition and Clinical Management.O&G open · 2026Review
- Telemedicine-assisted conservative management of placenta accreta spectrum: a case series from a tertiary center in Lithuania.BMC pregnancy and childbirth · 2026Article
- Crystal Vue-Estimated placental invasion area as a novel predictor of postpartum hemorrhage risk in placenta accreta spectrum disorders: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Placenta accreta spectrum is an increasingly common placental-related disorder diagnosed at birth when the placenta cannot be fully detached manually from the uterine wall, often requiring a surgical removal. Following a worldwide increase in caesarean delivery rates, more than 90% of cases are now found in patients with a history of caesarean delivery and an anterior low-lying placenta or a placenta previa. Accreta placentation is not a consequence of an inherently more aggressive cancer-like trophoblast but of a loss of the normal physiological cell signalling and physical regulatory mechanisms in the scar tissue, with higher-than-normal maternal blood velocity entering the intervillous space of the placenta, distortion of the corresponding lobules and a loss of the physiological site of detachment from the uterine wall. If unsuspected at the time of delivery, attempts to manually remove accreta tissue are often associated with major and sometimes uncontrollable bleeding. Patients with a high probability of placenta accreta spectrum at birth can be generally identified by prenatal ultrasonography, permitting management by a multidisciplinary team. Owing to the high risk of intraoperative and postpartum haemorrhage and damage to other pelvic organs, placenta previa accreta presents a management challenge, particularly in healthcare systems with limited resources. Involving the pregnant patient and their family in preparation for delivery reduces psychological morbidity associated with complex obstetric surgery. Standardized reporting protocols are essential to develop new management strategies. Further research is required to characterize the complex cellular changes at the uteroplacental interface in placenta accreta spectrum.
Indexed as
Identifiers
40473652What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.