ArticleBMC public health2025
Assessing spirometry, exhaled nitric oxide, and asthma symptoms score as instruments for respiratory health evaluation among women in a low socioeconomic context: a cross-sectional study.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma is a major public health burden worldwide and presents as a health service challenge in low-income countries with poor living conditions and limited access to healthcare services.
aimTo assess the relationship between asthma symptom scores, doctor-diagnosed current asthma (DDCA), fractional exhaled nitric oxide (FeNO) levels, and spirometry measurements as methods for assessing the respiratory health of adult women in rural and urban households in Zimbabwe.
methodsUsing a cross sectional study design, 790 adult women were recruited for the Household Air Pollution (HAP) and Lung Health study between March 2018 and December 2019 in Goromonzi and Harare communities in Zimbabwe. Using a validated interviewer-administered respiratory health questionnaire, we created the asthma symptom score with a cut-off point of ≥ 2 ([Formula: see text]implying none to modest symptoms and ≥ 2 suggesting moderate to severe symptoms) and DDCA categories based on responses to asthma related questions. Spirometry (n = 584) and FeNO (n = 258) measurements were performed, using standard validated techniques. Associations between spirometry z-scores, FeNO, asthma symptom score and the DDCA were analysed.
resultsThe 790 participants had an average age of 47.5 years (SD = 16.2). Asthma symptom score ≥ 2 was significantly associated with FeNO ≥ 50 ppb (p-value = 0.039) and the obstructive pattern (p-value = 0.018). Participants with DDCA had significantly increased FeNO (p-value < 0.001), a lower Forced expiratory volume in one second (FEV
conclusionThe results of our investigation indicated that those who with DDCA had significantly increased FeNO, and also DDCA was significantly associated with abnormal FEV
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