Evidence map›Paper›PMID 40474862›Full record

ReviewFuture medicinal chemistry2025

Latest developments in photosensitizers: improving stability, specificity and responsiveness.

Jiapeng Dong, Jiacheng Tang, Xinyi Li, Yaoxun Zeng, Xiang Su, Yan He, Xujie Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Enhancing Antibiotic Effect by Photodynamic: The Case ofAntibiotics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiapeng DongSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Jiacheng TangSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Xinyi LiSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Yaoxun ZengState Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Xiang SuSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Yan HeSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Xujie LiuSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.ORCID 0000-0001-8713-4287

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) has emerged as a promising anticancer strategy utilizing photosensitizers (PSs) to generate cytotoxic reactive oxygen species (ROS) upon light irradiation. This review highlights recent advancements in optimizing PSs through structural modifications, nanocarrier systems, and stimulus-responsive designs, aiming to enhance their stability, specificity, and responsiveness. Key strategies include chemical modifications (e.g. D-A type structures, shortening the polymethine chain or incorporation of rigid cyclic segments,

Indexed as

Antineoplastic AgentsNeoplasmsPhotosensitizing AgentsAnimalsHumansNanoparticlesPhotochemotherapyReactive Oxygen SpeciesTumor MicroenvironmentAntineoplastic AgentsPhotosensitizing AgentsReactive Oxygen Speciesphotodynamic therapyPhotosensitizerResponsivenessSpecificityStability

Identifiers

PMID40474862
PMCPMC12279273

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.