Evidence map›Paper›PMID 40475059›Full record

ArticleDermatology research and practice2025

M2 Macrophage and Extracellular Matrix Genes Are Enriched in High-Activity Lichen Planopilaris.

Ümmügülsüm Yıldız-Altay, Laura J Burns, Li-Chi Chen, Himanee Parag Dave, Mariko R Yasuda, Jillian M Richmond, Maryanne M Senna

Abstract read
In one paragraph

Article in Dermatology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ümmügülsüm Yıldız-AltayDepartment of Dermatology, Yale Medical School, New Haven, Connecticut 06510, USA.ORCID https://orcid.org/0000-0001-8774-9257
Laura J BurnsDepartment of Dermatology, UMass Chan Medical School, Worcester, Massachusetts 01605, USA.ORCID https://orcid.org/0000-0001-6310-9239
Li-Chi ChenDepartment of Dermatology, UMass Chan Medical School, Worcester, Massachusetts 01605, USA.ORCID https://orcid.org/0009-0004-1392-6395
Himanee Parag DaveDepartment of Dermatology, UMass Chan Medical School, Worcester, Massachusetts 01605, USA.ORCID https://orcid.org/0009-0004-2502-4786
Mariko R YasudaDepartment of Dermatology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.ORCID https://orcid.org/0009-0005-2675-6898
Jillian M RichmondDepartment of Dermatology, UMass Chan Medical School, Worcester, Massachusetts 01605, USA.ORCID https://orcid.org/0000-0003-1589-6770
Maryanne M SennaDepartment of Dermatology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.ORCID https://orcid.org/0000-0002-7813-520X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathophysiology of lichen planopilaris (LPP), a lymphocytic primary cicatricial alopecia, is largely unknown. We evaluated RNA expression of lesional scalp biopsies taken before and after 6 months of treatment monotherapy with oral hydroxychloroquine (HCQ), narrow band ultraviolet B (NB-UVB), or low level laser light therapy (LLLLT).

Indexed as

cicatricial alopeciafibrosishydroxychloroquinelaserlichen planopilarismacrophage polarizationNB-UVB

Identifiers

PMID40475059
PMCPMC12140823

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.