Evidence map›Paper›PMID 40475154›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Environmental Exposures and the Human Gut Resistome in Northwest Ecuador.

Irmarie Cotto, Ana Durán-Viseras, Kelsey J Jesser, Nicolette A Zhou, Caitlin Hemlock, Viviana Albán, April M Ballard, Christine S Fagnant-Sperati, Gwenyth O Lee, Janet K Hatt and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Irmarie CottoDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
Ana Durán-ViserasSchool of Civil and Environmental Engineering and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Kelsey J JesserDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
Nicolette A ZhouDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
Caitlin HemlockDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
Viviana AlbánDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
April M BallardDepartment of Population Health Sciences, Georgia State University, Atlanta, Georgia, USA.
Christine S Fagnant-SperatiDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
Gwenyth O LeeRutgers Global Health Institute, Rutgers University, New Brunswick, New Jersey, USA.
Janet K HattSchool of Civil and Environmental Engineering and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Charlotte RoyerSchool of Civil and Environmental Engineering and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Joseph N S EisenbergDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Gabriel TruebaInstituto de Microbiologia, Universidad San Francisco de Quito, Quito, Ecuador.
Konstantinos T KonstantinidisSchool of Civil and Environmental Engineering and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Karen LevyDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
Erica R FuhrmeisterDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Gut microbiome, enteric infections and child growth across a rurual urban gradientR01AI137679 · NIAID · UNIVERSITY OF WASHINGTON · PI EISENBERG, JOSEPH N. S., LEVY, KAREN · 2018 to 2023
$5.3M
Enteric Pathogen Force of Infection among Children using SerologyR01AI162867 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ARNOLD, BENJAMIN F · 2021 to 2025
$3.7M
NIAID NIH HHS R01 AI137679NIAID NIH HHS R01 AI162867NIEHS NIH HHS P30 ES007033
6 · The paper itself

Abstract

Inadequate water, sanitation, and hygiene (WASH) infrastructure may increase exposure to antimicrobial resistance (AMR). In addition, close human-animal interactions and unregulated antibiotic use in livestock facilitate the spread of resistant bacteria. We used metagenomic sequence data and multivariate models to assess how animal exposure and WASH conditions affect the gut resistome and microbiome in 53 pregnant women and 84 children in Ecuador.

Identifiers

PMID40475154
PMCPMC12140539

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.