Evidence map›Paper›PMID 40475168›Full record

ReviewMolecular syndromology2025

The Opportunities and Challenges in the Molecular Mechanism Research of Congenital Heart Disease: A Review.

Mingwei Li, Shuangxing Wang, Hui Zhang, Bing Meng, Yongjie Wu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular syndromology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mingwei LiDepartment of Cardiac Surgery, Children's Hospital of Capital Institute of Pediatrics, Beijing, China.
Shuangxing WangDepartment of Cardiac Surgery, Children's Hospital of Capital Institute of Pediatrics, Beijing, China.
Hui ZhangDepartment of Cardiac Surgery, Children's Hospital of Capital Institute of Pediatrics, Beijing, China.
Bing MengDepartment of Cardiac Surgery, Children's Hospital of Capital Institute of Pediatrics, Beijing, China.
Yongjie WuDepartment of Cardiac Surgery, Children's Hospital of Capital Institute of Pediatrics, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Advanced molecular mechanism research incorporated with multidisciplinary collaborations on congenital heart disease has prompted new insight into its cause, development, and outcomes. Summary: This literature review aims to comprehensively examine the genetic molecular mechanisms of congenital heart disease and explain current prospects and challenges in this field. Through a systematic exploration of etiology, embryology, clinical outcomes, algorithms, and ethics, we seek to shed light on the path toward improved diagnostics, treatments, and outcomes for patients. Key Message: Collaboration among genetic researchers, clinicians, data scientists, ethicists, and policymakers is crucial to address challenges and translate research findings into tangible benefits for CHD patients.

Indexed as

Congenital heart diseaseGenetic researchLiterature reviewMolecular mechanism

Identifiers

PMID40475168
PMCPMC12136570

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.