Evidence map›Paper›PMID 40475539›Full record

ArticlebioRxiv : the preprint server for biology2025

Electrical Stimulation Rejuvenates Tunicates: Altered Stem Cell and Immune Activity.

Jos Domen, Yotam Voskoboynik, Tom Levy, Erica M Domen, Katherine J Ishizuka, Karla J Palmeri, Chiara Anselmi, Thomas Rolander, Norma F Neff, Angela M Detweiler and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jos DomenBiology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950, USA.
Yotam VoskoboynikDepartment of Bioinformatics and System Biology, Jacobs School of Engineering, University of California, San Diego, San Diego, CA, USA.
Tom LevyBiology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950, USA.
Erica M DomenUniversity of California Berkeley, Berkeley, CA 94704, USA.
Katherine J IshizukaBiology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950, USA.
Karla J PalmeriBiology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950, USA.
Chiara AnselmiBiology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950, USA.
Thomas RolanderBiology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950, USA.
Norma F NeffChan Zuckerberg Biohub SF, San Francisco CA 94158, USA.
Angela M DetweilerChan Zuckerberg Biohub SF, San Francisco CA 94158, USA.
Irving L WeissmanInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Kimberly L GandyBiology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950, USA.
Debashis SahooDepartment of Pediatrics, University of California San Diego, CA, USA.
Ayelet VoskoboynikBiology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950, USA.ORCID 0000-0001-9570-1392

Funding

Evolutionary Conserved Mechanisms that Control Central Nervous System Development Regeneration and DegenerationR01AG076908 · STANFORD UNIVERSITY · 2025 to 2025
$378k
NIA NIH HHS R01 AG076908
6 · The paper itself

Abstract

Applicable methods of rejuvenating organisms and improving resistance to environmental stimuli are needed. During attempts to synchronize heart rates in unhealthy colonial chordates, we observed morphological rejuvenation. While the importance of endogenously generated bioelectric currents in development is well-established

Identifiers

PMID40475539
PMCPMC12139841

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.