ArticleJournal of Taibah University Medical Sciences2025
Histological evaluation of effects of krill oil and eucalyptus oil on bone healing in rats.
Article in Journal of Taibah University Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bone defect repair is a significant challenge in orthopedic medicine. Objectives: This study assessed the effectiveness of applying krill oil locally as an osteoinducer in bone healing, and the impact of eucalyptus oil as a stimulant for healing bone defects. Subjects and methods: In this study, 48 albino male rats weighing 300-400 g and aged 6-8 months were used, where their environment was carefully monitored, including the amounts of water and food consumed. The experimental test site was the side of the right tibia and the control site was on the left tibia. The treatment was performed on the inner side of the tibia. Bone deficit treatment on the control site involved applying 1 μL of distilled water topically once each day. The experimental treatments were tested in three subgroups: group I received daily local application with 1 μL of krill oil, group II received daily local application with 1 μL of eucalyptus oil, and group III received daily local application with 1 μL of-a combination of krill oil and eucalyptus oil. Six rats were sacrificed at 7 and 14 days after surgery, with 12 rats in each group. Results: Osteoid tissue development and dramatic increases in the numbers of bone cells were observed after local administration of either krill oil or eucalyptus oil separately, or both substances combined, to a tibia lesion. Notable changes in the area of bone marrow occurred, with increases in the trabecular bone area and gradual decreases in the trabecular bone number. Conclusion: Combined treatment with krill oil and eucalyptus oil has therapeutic potential for accelerating the mending of bone deformities. Krill and eucalyptus oils can affect osteogenesis and angiogenesis processes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.