ArticleMedical journal of the Islamic Republic of Iran2024
Peripheral Arterial Disease is Associated with Sensorimotor Peripheral Neuropathy in People with Type 2 Diabetes.
Article in Medical journal of the Islamic Republic of Iran, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Development and Validation of a Machine Learning-Based Predictive Model for Peripheral Neuropathy Risk in Elderly Patients with Type 2 Diabetes.Risk management and healthcare policy · 2026Article
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5 authors.
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Abstract
Background: Micro- and macro-vascular complications of diabetes seem to be interconnected. This study aimed to evaluate the association between peripheral arterial diseases (PAD) and diabetic sensorimotor peripheral neuropathy (DSPN). Methods: This cross-sectional study was conducted among 748 people with type 2 diabetes (T2DM) referred to a tertiary care center between 2017 and 2022. PAD was defined as Ankle-brachial index (ABI) ≤ 0.9. Loss of protective sensation (LOPS) was applied for the detection of DSPN. Logistic regression analysis was used to determine the association between PAD and DSPN. Results: The mean age of the participants was 59.6 (±8.8) years, and the median duration of diabetes was 10 (5-16) years. LOPS was detected in 491 individuals (65.6%). ABI ≤ 0.9 was associated with a significantly higher risk of LOPS (OR: 3.65, 95% Confidence Interval (CI): 1.97- 6.74). In addition, every 0.1 decrease in ABI increased the risk of LOPS by 21% (95%CI: 10- 34%). Toe brachial index (TBI) ≤0.7 was also associated with a significantly higher risk of LOPS (OR: 1.77, 95%CI: 1.28- 2.46). Each 0.1 decrease in TBI increased the risk of LOPS by 19% (95%CI: 10- 28%). Conclusion: PAD is strongly associated with DSPN. Assessment of DSPN could be considered in the presence of PAD.
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