Evidence map›Paper›PMID 40478314›Full record

SynthesisBrain tumor pathology2025

Triple sellar collision lesion: a unique case of pituitary adenoma, Rathke cleft cyst, and xanthogranuloma-case report and systematic review of the literature.

Miguel A Del Toro-Colín, Martha Tena-Suck, Alberto Santiago-Balmaseda, Citlalteptl Salinas-Lara, Germán Velázquez-Garcia, Maria de Lourdes Aguilar-Gómez, Elsa Yazmín León-Marroquín, Carlos Sánchez-Garibay, Alma Ortíz-Plata, Roger Carrillo-Meza and 3 more

Abstract readCase ReportsSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Brain tumor pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Miguel A Del Toro-Colín *Laboratorio de Patogénesis Molecular, Laboratorio 4, Edificio A4, Facultad de Estudios Superiores Iztacala, Carrera Médico Cirujano, Universidad Nacional Autónoma de México, 54090, Tlalnepantla, Edomex, Mexico.
Martha Tena-Suck *Departamento de Neuropatología, Instituto Nacional de Neurología y Neurocirugía "Dr. Manuel Velasco Suárez", 14269, Ciudad de Mexico, Mexico.
Alberto Santiago-Balmaseda *Laboratorio de Patogénesis Molecular, Laboratorio 4, Edificio A4, Facultad de Estudios Superiores Iztacala, Carrera Médico Cirujano, Universidad Nacional Autónoma de México, 54090, Tlalnepantla, Edomex, Mexico.
Citlalteptl Salinas-LaraDepartamento de Neuropatología, Instituto Nacional de Neurología y Neurocirugía "Dr. Manuel Velasco Suárez", 14269, Ciudad de Mexico, Mexico.
Germán Velázquez-GarciaCarrera de Médico Cirujano Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autonoma de México, Iztapalapa, 09239, CDMX, México.
Maria de Lourdes Aguilar-GómezRed MEDICI, Facultad de Estudios Superiores Iztacala, Carrera Médico Cirujano, Universidad Nacional Autónoma de México, 54090, Tlalnepantla, Edomex, Mexico.
Elsa Yazmín León-MarroquínDepartamento de Física Médica, Hospital de Oncología Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, CDMX, México.
Carlos Sánchez-GaribayDepartamento de Neuropatología, Instituto Nacional de Neurología y Neurocirugía "Dr. Manuel Velasco Suárez", 14269, Ciudad de Mexico, Mexico.
Alma Ortíz-PlataDepartamento de Patología Experimental, Instituto Nacional de Neurología y Neurocirugía "Dr. Manuel Velasco Suárez", Ciudad de Mexico, 14269, Mexico.
Roger Carrillo-MezaDepartamento de Neuroimagen, Instituto Nacional de Neurología y Neurocirugía "Dr. Manuel Velasco Suárez", Ciudad de Mexico, 14269, Mexico.
Noemi Gelista-HerreraDepartamento de Neuropatología, Instituto Nacional de Neurología y Neurocirugía "Dr. Manuel Velasco Suárez", 14269, Ciudad de Mexico, Mexico.
Lesly Hernández-RoqueRed MEDICI, Facultad de Estudios Superiores Iztacala, Carrera Médico Cirujano, Universidad Nacional Autónoma de México, 54090, Tlalnepantla, Edomex, Mexico.
Luis O Soto-RojasLaboratorio de Patogénesis Molecular, Laboratorio 4, Edificio A4, Facultad de Estudios Superiores Iztacala, Carrera Médico Cirujano, Universidad Nacional Autónoma de México, 54090, Tlalnepantla, Edomex, Mexico. oskarsoto123@unam.mx.ORCID http://orcid.org/0000-0002-5013-3608

Funding

UNAM-PAPIIT IA205423
6 · The paper itself

Abstract

The coexistence of three lesions in the sellar region is exceedingly rare. Only two cases with three histopathologically distinct lesions have been reported. However, here, we present a unique case of a 54-year-old female with pituitary adenoma (PA), xanthogranulomatous hypophysitis (XGH), and a Rathke cleft cyst (RCC). Clinically, the patient manifested symptoms of mass compression, such as moderate-intensity headaches and progressive visual acuity decrease. Relevant endocrinological evaluation revealed elevated free thyroxine levels without clinical manifestations. MRI revealed a suprasellar mass compatible with a macroadenoma. The patient underwent transsphenoidal endoscopic resection, resulting in a non-functional macroadenoma with associated XGH due to the rupture of RCC. Furthermore, in this article, we analyze the possible mechanisms involved in the pathogenesis of these lesions, emphasizing the type of spectrum to which they belong and the manifestations present.

Indexed as

AdenomaCentral Nervous System CystsGranulomaPituitary NeoplasmsSella TurcicaXanthomatosisFemaleHumansHypophysitisMagnetic Resonance ImagingMiddle AgedCase reportPituitary adenomaRathke cleft cystSellar collision lesionsXanthogranulomatous hypophysitis

Identifiers

PMID40478314
PMCPMC12518419

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.