Evidence map›Paper›PMID 40479575›Full record

ArticleAging and disease2025

Risk Factors for Oropharyngeal Dysphagia in Older Adults - Evidence from Consorci Sanitari Del Maresme and Mataró University Hospital, Catalonia, Spain.

Lucilla Guidotti, Jorge Iván Castañeda-Maldonado, Marta Santiago, Pere Clavé, Omar Ortega

Abstract read
In one paragraph

Article in Aging and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucilla GuidottiGastrointestinal Physiology Laboratory, Department of Surgery, Hospital Universitari de Mataró, Consorci Sanitari del Maresme Universitat Autònoma de Barcelona, Barcelona, Spain.
Jorge Iván Castañeda-MaldonadoGastrointestinal Physiology Laboratory, Department of Surgery, Hospital Universitari de Mataró, Consorci Sanitari del Maresme Universitat Autònoma de Barcelona, Barcelona, Spain.
Marta SantiagoGastrointestinal Physiology Laboratory, Department of Surgery, Hospital Universitari de Mataró, Consorci Sanitari del Maresme Universitat Autònoma de Barcelona, Barcelona, Spain.
Pere ClavéGastrointestinal Physiology Laboratory, Department of Surgery, Hospital Universitari de Mataró, Consorci Sanitari del Maresme Universitat Autònoma de Barcelona, Barcelona, Spain.
Omar OrtegaGastrointestinal Physiology Laboratory, Department of Surgery, Hospital Universitari de Mataró, Consorci Sanitari del Maresme Universitat Autònoma de Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oropharyngeal dysphagia (OD) is a highly prevalent geriatric syndrome that remains underdiagnosed and undertreated, often resulting in severe nutritional and respiratory complications with poor clinical outcomes. Its risk factors are still not well defined, representing a critical gap in efforts to understand its pathophysiology, prevent the condition and reduce its associated complications. To analyze data from comprehensive studies conducted in a single-center setting to ascertain the major risk factors associated with OD as a geriatric syndrome. A retrospective analysis was conducted, encompassing a review of prior studies, including a cohort of 7,272 older patients with OD at Consorci Sanitari del Maresme, Catalonia, Spain, presented as a narrative review. The study presents data using odds ratios (OR) and p-values from univariate and multivariate analyses to show the association of OD with its main risk factors in different phenotypes of older patients with OD (independently living, acute hospitalized, and with pneumonia, dementia, COVID-19, stroke). Quality of studies was assessed with ROBINS-I-V2. Outcome (risk factors) quality was assessed with GRADE. Thirteen studies (2010-2022) were reviewed. OD exhibited significant associations with 8 main groups of risk factors among older patients from diverse phenotypes. The main risk factors were impaired functionality (OR:2.24-12.7), aging (OR:1.05-5.16) and malnutrition (OR:2.46-5.16). Comorbidities, respiratory disease, neurological impairments, geriatric syndromes and pharmacological treatments were also significantly associated with OD (OR:1.02-15.52). The quality of the included studies and variables was mainly moderate. OD is a geriatric syndrome associated with several risk factors across multiple phenotypes of older patients. These findings highlight the critical need for early identification and targeted prevention of key risk factors for OD to improve clinical outcomes and reduce the burden of this underdiagnosed geriatric syndrome.

Indexed as

Deglutition DisordersAgedAged, 80 and overCOVID-19FemaleHospitals, UniversityHumansMaleRetrospective StudiesRisk FactorsSARS-CoV-2Spain

Identifiers

PMID40479575
PMCPMC13061561

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.